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Ubiquitin-specific protease 15

 F4I642_ARATH            Unreviewed;       928 AA.
F4I642;
28-JUN-2011, integrated into UniProtKB/TrEMBL.
28-JUN-2011, sequence version 1.
05-DEC-2018, entry version 60.
SubName: Full=Ubiquitin-specific protease 15 {ECO:0000313|EMBL:AEE29543.1};
Name=UBP15 {ECO:0000313|EMBL:AEE29543.1};
Synonyms=UBIQUITIN-SPECIFIC PROTEASE 15 {ECO:0000313|EMBL:AEE29543.1},
ubiquitin-specific protease 15 {ECO:0000313|EMBL:AEE29543.1};
OrderedLocusNames=At1g17110 {ECO:0000313|Araport:AT1G17110,
ECO:0000313|EMBL:AEE29543.1};
ORFNames=F20D23.20 {ECO:0000313|EMBL:AEE29543.1},
F20D23_20 {ECO:0000313|EMBL:AEE29543.1};
Arabidopsis thaliana (Mouse-ear cress).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
Arabidopsis.
NCBI_TaxID=3702 {ECO:0000313|EMBL:AEE29543.1, ECO:0000313|Proteomes:UP000006548};
[1] {ECO:0000313|EMBL:AEE29543.1, ECO:0000313|Proteomes:UP000006548}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
PubMed=11130712; DOI=10.1038/35048500;
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S.,
White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y.,
Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W.,
Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K.,
Dunn P., Etgu P., Feldblyum T.V., Feng J., Fong B., Fujii C.Y.,
Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L.,
Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E.,
Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B.,
Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X.,
Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J.,
Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G.,
Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H.,
Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H.,
Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T.,
Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G.,
Fraser C.M., Venter J.C., Davis R.W.;
"Sequence and analysis of chromosome 1 of the plant Arabidopsis
thaliana.";
Nature 408:816-820(2000).
[2] {ECO:0000313|Proteomes:UP000006548}
GENOME REANNOTATION.
STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
PubMed=27862469; DOI=10.1111/tpj.13415;
Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
Town C.D.;
"Araport11: a complete reannotation of the Arabidopsis thaliana
reference genome.";
Plant J. 89:789-804(2017).
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EMBL; CP002684; AEE29543.1; -; Genomic_DNA.
RefSeq; NP_001185019.1; NM_001198090.2.
UniGene; At.48199; -.
ProteinModelPortal; F4I642; -.
SMR; F4I642; -.
EnsemblPlants; AT1G17110.2; AT1G17110.2; AT1G17110.
GeneID; 838281; -.
Gramene; AT1G17110.2; AT1G17110.2; AT1G17110.
Araport; AT1G17110; -.
TAIR; locus:2020412; AT1G17110.
eggNOG; KOG1865; Eukaryota.
eggNOG; ENOG410XQ92; LUCA.
OrthoDB; EOG093603PC; -.
Proteomes; UP000006548; Chromosome 1.
ExpressionAtlas; F4I642; baseline and differential.
GO; GO:0005737; C:cytoplasm; IDA:TAIR.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005634; C:nucleus; IDA:TAIR.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0004843; F:thiol-dependent ubiquitin-specific protease activity; IDA:TAIR.
GO; GO:0008283; P:cell proliferation; IMP:TAIR.
GO; GO:0009908; P:flower development; IMP:TAIR.
GO; GO:0010154; P:fruit development; IMP:TAIR.
GO; GO:0048366; P:leaf development; IMP:TAIR.
GO; GO:0016579; P:protein deubiquitination; IDA:TAIR.
GO; GO:0048364; P:root development; IMP:TAIR.
GO; GO:0048367; P:shoot system development; IMP:TAIR.
GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
InterPro; IPR038765; Papain_like_cys_pep_sf.
InterPro; IPR001394; Peptidase_C19_UCH.
InterPro; IPR018200; USP_CS.
InterPro; IPR028889; USP_dom.
InterPro; IPR002893; Znf_MYND.
Pfam; PF00443; UCH; 1.
Pfam; PF01753; zf-MYND; 1.
SUPFAM; SSF54001; SSF54001; 1.
PROSITE; PS00972; USP_1; 1.
PROSITE; PS50235; USP_3; 1.
PROSITE; PS50865; ZF_MYND_2; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000006548};
Hydrolase {ECO:0000313|EMBL:AEE29543.1};
Membrane {ECO:0000256|SAM:Phobius};
Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00134,
ECO:0000256|SAAS:SAAS00513840};
Protease {ECO:0000313|EMBL:AEE29543.1};
Reference proteome {ECO:0000313|Proteomes:UP000006548};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius};
Zinc {ECO:0000256|PROSITE-ProRule:PRU00134,
ECO:0000256|SAAS:SAAS00513840};
Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00134,
ECO:0000256|SAAS:SAAS00513840}.
TRANSMEM 7 27 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 130 167 MYND-type. {ECO:0000259|PROSITE:PS50865}.
DOMAIN 442 748 USP. {ECO:0000259|PROSITE:PS50235}.
SEQUENCE 928 AA; 104063 MW; 0D46BBF0CDB0670C CRC64;
MLEPRGADIP ILFLVLVVLP VVAYILLGKW SNISEKRVRA NLLAQMAAEE ALRAETVVNA
DRGVRFESVA TENRAQRTRT KTVSAGGGAV RAEFDAGARE TVAEQRSDSV TATCGVTVVA
PVNNNELHVC ARCFGPAKTR CSRCKSVRYC SGKCQIIHWR VAHKDECVPV ESCSSSSERV
SFEKDSVLYD HGMDSTMYSN NTTQAAKGKT SKSSVDFASL GISQNDITPQ INTQGRKSVG
KQHSSKANRE SCRRDSATVF DSSDEAASAG GDNKTSHIKH KSRGNSYAAE TNPRRHSVDS
SAVQMNGQSF VSGMQESHKH ENNLGVRSSF GCPNTQYPSN GTRTATLPRT GINKSGEQSC
TETSKKGQVA AVSKTVRSKD TGISEESNGI SSTMGIMKMM GLRNSTKHDD RYKNLKVSSL
MLFPYEEFLK FFQCEVFDLS PRGLVNCGNS CYANAVLQSL TCTKPLVAYL LRRSHSRSCS
GKDWCLMCEL EQHVMMLRES GGPLSASRIL SHMRSINCQI GDGSQEDAHE FLRLLVASMQ
SICLERLGGE TKVDPRLQET TLVQHMFGGR LRSKVKCLRC DHESERYENI MDLTLEIYGW
VESLQDALTQ FTRPEDLDGE NMYRCSRCAG YVRARKELSI HEAPNILTIV LKRFQEGRYG
KINKCISFPE MLDMIPFMTR TGDVPPLYML YAVIVHLDTL NASFSGHYIS YVKDLRGNWY
RIDDSEIHPV PMTQVMSEGA YMLFYMRSYP RPQRGEHNGK APVHHSQPRN EMKEQRKPVN
RFKPRADHKN TESSSSEWSL FTSSDEASFT TESTRDSFST IDYTDVCHVV DSSSPFAIFN
NVYHNVEPSP HNTVACRMFS GTKPETRYFV EQETNHNNTV VLDATPSLYP IPAPYPPHDY
YDQSMYVNYE TNPEFNNGQD QDRTYSYW


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