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Uncharacterized HTH-type transcriptional regulator TtgW

 TTGW_PSEPT              Reviewed;         134 AA.
Q93PU7;
19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
01-OCT-2002, sequence version 2.
10-MAY-2017, entry version 69.
RecName: Full=Uncharacterized HTH-type transcriptional regulator TtgW;
Name=ttgW;
Pseudomonas putida (strain DOT-T1E).
Plasmid pGRT1.
Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
Pseudomonadaceae; Pseudomonas.
NCBI_TaxID=1196325;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=DOT-T1E;
PubMed=11395460; DOI=10.1128/JB.183.13.3967-3973.2001;
Rojas A., Duque E., Mosqueda G., Golden G., Hurtado A., Ramos J.L.,
Segura A.;
"Three efflux pumps are required to provide efficient tolerance to
toluene in Pseudomonas putida DOT-T1E.";
J. Bacteriol. 183:3967-3973(2001).
[2]
SEQUENCE REVISION.
STRAIN=DOT-T1E;
Rojas A.M., Segura A., Ramos J.L.;
Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=DOT-T1E;
PubMed=21605303; DOI=10.1111/j.1462-2920.2011.02492.x;
Molina L., Duque E., Gomez M.J., Krell T., Lacal J., Garcia-Puente A.,
Garcia V., Matilla M.A., Ramos J.L., Segura A.;
"The pGRT1 plasmid of Pseudomonas putida DOT-T1E encodes functions
relevant for survival under harsh conditions in the environment.";
Environ. Microbiol. 13:2315-2327(2011).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=DOT-T1E;
PubMed=23815283; DOI=10.1111/1751-7915.12061;
Udaondo Z., Molina L., Daniels C., Gomez M.J., Molina-Henares M.A.,
Matilla M.A., Roca A., Fernandez M., Duque E., Segura A., Ramos J.L.;
"Metabolic potential of the organic-solvent tolerant Pseudomonas
putida DOT-T1E deduced from its annotated genome.";
Microb. Biotechnol. 6:598-611(2013).
[5]
OPERON ORGANIZATION, INDUCTION, AND CHARACTERIZATION.
STRAIN=DOT-T1E;
PubMed=12896994; DOI=10.1128/JB.185.16.4755-4763.2003;
Rojas A., Segura A., Guazzaroni M.E., Teran W., Hurtado A.,
Gallegos M.T., Ramos J.L.;
"In vivo and in vitro evidence that TtgV is the specific regulator of
the TtgGHI multidrug and solvent efflux pump of Pseudomonas putida.";
J. Bacteriol. 185:4755-4763(2003).
-!- FUNCTION: Unknown, does not seem to be involved in regulation of
the ttgGHI or ttgVW operons.
-!- INDUCTION: The ttgVW operon is induced by toluene and styrene, but
not by the antibiotics carbenicillin, chloramphenicol, nalidixic
acid, tetracycline or gentamicin. {ECO:0000269|PubMed:12896994}.
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EMBL; HM626202; AAK69561.2; -; Genomic_DNA.
RefSeq; WP_014003967.1; NC_015855.1.
RefSeq; YP_004750621.1; NC_015855.1.
ProteinModelPortal; Q93PU7; -.
SMR; Q93PU7; -.
GeneID; 11002018; -.
Proteomes; UP000006503; Plasmid pGRT1.
GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
InterPro; IPR009057; Homeobox-like.
InterPro; IPR001647; HTH_TetR.
Pfam; PF00440; TetR_N; 1.
PRINTS; PR00455; HTHTETR.
SUPFAM; SSF46689; SSF46689; 1.
PROSITE; PS01081; HTH_TETR_1; 1.
PROSITE; PS50977; HTH_TETR_2; 1.
1: Evidence at protein level;
Complete proteome; DNA-binding; Plasmid; Transcription;
Transcription regulation.
CHAIN 1 134 Uncharacterized HTH-type transcriptional
regulator TtgW.
/FTId=PRO_0000070626.
DOMAIN 10 70 HTH tetR-type. {ECO:0000255|PROSITE-
ProRule:PRU00335}.
DNA_BIND 33 52 H-T-H motif. {ECO:0000255|PROSITE-
ProRule:PRU00335}.
SEQUENCE 134 AA; 15030 MW; 69F70FDAF7DE8E4B CRC64;
MARKTAAEAK ETRQRIIDAA LEVFVAQGVP DATLDQIARK AGVTRGAVYW HFNGKLEVLQ
AVLASRQHPL ELDFTPDLGI ERSWEAVVVA MLDAVHSPQS KQFSEILIYQ GLDESGLIHN
RMVQASDRFL QYIR


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