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Uncharacterized protein

 G1L6K8_AILME            Unreviewed;       307 AA.
G1L6K8;
19-OCT-2011, integrated into UniProtKB/TrEMBL.
19-OCT-2011, sequence version 1.
27-SEP-2017, entry version 37.
SubName: Full=Caudal type homeobox 2 {ECO:0000313|Ensembl:ENSAMEP00000002523};
Name=CDX2 {ECO:0000313|Ensembl:ENSAMEP00000002523};
Ailuropoda melanoleuca (Giant panda).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae;
Ailuropoda.
NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000002523, ECO:0000313|Proteomes:UP000008912};
[1] {ECO:0000313|Ensembl:ENSAMEP00000002523}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=20010809; DOI=10.1038/nature08696;
Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q.,
Li B., Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H.,
Jian M., Li J., Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z.,
Ryder O.A., Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X.,
Guo X., Wang B., Hou R., Shen F., Mu B., Ni P., Lin R., Qian W.,
Wang G., Yu C., Nie W., Wang J., Wu Z., Liang H., Min J., Wu Q.,
Cheng S., Ruan J., Wang M., Shi Z., Wen M., Liu B., Ren X., Zheng H.,
Dong D., Cook K., Shan G., Zhang H., Kosiol C., Xie X., Lu Z.,
Zheng H., Li Y., Steiner C.C., Lam T.T., Lin S., Zhang Q., Li G.,
Tian J., Gong T., Liu H., Zhang D., Fang L., Ye C., Zhang J., Hu W.,
Xu A., Ren Y., Zhang G., Bruford M.W., Li Q., Ma L., Guo Y., An N.,
Hu Y., Zheng Y., Shi Y., Li Z., Liu Q., Chen Y., Zhao J., Qu N.,
Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X., Vinar T., Wang Y.,
Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y., Wang X.,
Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H.,
Wang J., Wang J.;
"The sequence and de novo assembly of the giant panda genome.";
Nature 463:311-317(2010).
[2] {ECO:0000313|Ensembl:ENSAMEP00000002523}
IDENTIFICATION.
Ensembl;
Submitted (SEP-2011) to UniProtKB.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
ProRule:PRU00108, ECO:0000256|RuleBase:RU000682,
ECO:0000256|SAAS:SAAS00860360}.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSAMEP00000002523}.
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EMBL; ACTA01164453; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ACTA01172451; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ACTA01180449; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ACTA01188447; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9646.ENSAMEP00000002523; -.
Ensembl; ENSAMET00000002633; ENSAMEP00000002523; ENSAMEG00000002400.
eggNOG; KOG0848; Eukaryota.
eggNOG; ENOG4111W2J; LUCA.
GeneTree; ENSGT00530000063388; -.
InParanoid; G1L6K8; -.
OMA; GPSWPSP; -.
OrthoDB; EOG091G0LXJ; -.
TreeFam; TF351605; -.
Proteomes; UP000008912; Unassembled WGS sequence.
GO; GO:0000794; C:condensed nuclear chromosome; IEA:Ensembl.
GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
GO; GO:0043234; C:protein complex; IEA:Ensembl.
GO; GO:0017053; C:transcriptional repressor complex; IEA:Ensembl.
GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IEA:Ensembl.
GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
GO; GO:0001227; F:transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding; IEA:Ensembl.
GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
GO; GO:0008333; P:endosome to lysosome transport; IEA:Ensembl.
GO; GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IEA:Ensembl.
GO; GO:0060575; P:intestinal epithelial cell differentiation; IEA:Ensembl.
GO; GO:0060711; P:labyrinthine layer development; IEA:Ensembl.
GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
GO; GO:0014807; P:regulation of somitogenesis; IEA:Ensembl.
GO; GO:0035019; P:somatic stem cell population maintenance; IEA:Ensembl.
GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
CDD; cd00086; homeodomain; 1.
InterPro; IPR006820; Caudal_activation_dom.
InterPro; IPR009057; Homeobox-like.
InterPro; IPR017970; Homeobox_CS.
InterPro; IPR001356; Homeobox_dom.
InterPro; IPR020479; Homeobox_metazoa.
InterPro; IPR000047; HTH_motif.
Pfam; PF04731; Caudal_act; 1.
Pfam; PF00046; Homeobox; 1.
PRINTS; PR00024; HOMEOBOX.
PRINTS; PR00031; HTHREPRESSR.
SMART; SM00389; HOX; 1.
SUPFAM; SSF46689; SSF46689; 1.
PROSITE; PS00027; HOMEOBOX_1; 1.
PROSITE; PS50071; HOMEOBOX_2; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000008912};
DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860283};
Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860291};
Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860284};
Reference proteome {ECO:0000313|Proteomes:UP000008912}.
DOMAIN 184 244 Homeobox. {ECO:0000259|PROSITE:PS50071}.
DNA_BIND 186 245 Homeobox. {ECO:0000256|PROSITE-
ProRule:PRU00108}.
SEQUENCE 307 AA; 33246 MW; 6E99EEA26E5BA3AC CRC64;
MYVSYLLDKD VSMYPSSVRH SGGLNLAPQN FVSPPQYPDY GGYXAAANLD SAQSPGPSWP
AAYGAPLRED WNGYAPGVQS KAGGLGARSR GSPPVSAEGE GAESLMHAYV QETCPRDVPA
DILGLPDCGG SLVTGLPLLV SGCVSKLGRN QPNPGPLGRW RKRNGPWVRE FSALTSPSST
VKTRTKDKYR VVYTDHQRLE LEKEFHYSRY ITIRRKAELA ATLGLSERQV KIWFQNRRAK
ERKINKKKLQ QQQQQPQPAP PPQPQPGPLR SVPEPLSPVS ALQGSVPGPV PGVLGPAAGV
LNPTVTQ


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