Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Uncharacterized protein

 G7NTZ0_MACFA            Unreviewed;       442 AA.
G7NTZ0;
25-JAN-2012, integrated into UniProtKB/TrEMBL.
25-JAN-2012, sequence version 1.
05-DEC-2018, entry version 44.
RecName: Full=Transforming growth factor beta {ECO:0000256|PIRNR:PIRNR001787};
Name=TGFB2 {ECO:0000313|Ensembl:ENSMFAP00000005501};
ORFNames=EGM_01384 {ECO:0000313|EMBL:EHH50534.1};
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
NCBI_TaxID=9541 {ECO:0000313|Proteomes:UP000009130};
[1] {ECO:0000313|EMBL:EHH50534.1, ECO:0000313|Proteomes:UP000009130}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CE-4 {ECO:0000313|EMBL:EHH50534.1};
PubMed=22002653; DOI=10.1038/nbt.1992;
Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N.,
Li Q., Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P.,
Huang Z., Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T.,
Huang Y., Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D.,
Li B., Liu X., Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X.,
Li Y., Wang W., Katze M.G., Su B., Nielsen R., Yang H., Wang J.,
Wang X., Wang J.;
"Genome sequencing and comparison of two nonhuman primate animal
models, the cynomolgus and Chinese rhesus macaques.";
Nat. Biotechnol. 29:1019-1023(2011).
[2] {ECO:0000313|Ensembl:ENSMFAP00000005501}
NUCLEOTIDE SEQUENCE.
Huang N.-L., Huang M.-D., Chen T.-L.L., Huang A.H.;
Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|Ensembl:ENSMFAP00000005501}
IDENTIFICATION.
Ensembl;
Submitted (FEB-2018) to UniProtKB.
-!- SUBUNIT: Homodimer; disulfide-linked.
{ECO:0000256|PIRNR:PIRNR001787}.
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|PIRNR:PIRNR001787,
ECO:0000256|SAAS:SAAS00581915}.
-!- SIMILARITY: Belongs to the TGF-beta family.
{ECO:0000256|PIRNR:PIRNR001787, ECO:0000256|RuleBase:RU000354,
ECO:0000256|SAAS:SAAS00581927}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AQIA01001702; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AQIA01001703; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CM001276; EHH50534.1; -; Genomic_DNA.
RefSeq; XP_005540930.1; XM_005540873.2.
RefSeq; XP_015305617.1; XM_015450131.1.
RefSeq; XP_015305620.1; XM_015450134.1.
UniGene; Mfa.4010; -.
ProteinModelPortal; G7NTZ0; -.
Ensembl; ENSMFAT00000024178; ENSMFAP00000005501; ENSMFAG00000002417.
GeneID; 101925182; -.
KEGG; mcf:101925182; -.
CTD; 7042; -.
GeneTree; ENSGT00940000157390; -.
KO; K13376; -.
Proteomes; UP000009130; Chromosome 1.
GO; GO:0062023; C:collagen-containing extracellular matrix; IEA:Ensembl.
GO; GO:0031012; C:extracellular matrix; ISS:AgBase.
GO; GO:0005576; C:extracellular region; ISS:AgBase.
GO; GO:0005615; C:extracellular space; ISS:AgBase.
GO; GO:0001540; F:amyloid-beta binding; ISS:AgBase.
GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-UniRule.
GO; GO:0042803; F:protein homodimerization activity; ISS:AgBase.
GO; GO:0005102; F:signaling receptor binding; ISS:AgBase.
GO; GO:0005160; F:transforming growth factor beta receptor binding; ISS:AgBase.
GO; GO:0005114; F:type II transforming growth factor beta receptor binding; ISS:AgBase.
GO; GO:0034714; F:type III transforming growth factor beta receptor binding; ISS:AgBase.
GO; GO:0032147; P:activation of protein kinase activity; ISS:AgBase.
GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; ISS:AgBase.
GO; GO:0060038; P:cardiac muscle cell proliferation; ISS:AgBase.
GO; GO:0010002; P:cardioblast differentiation; ISS:AgBase.
GO; GO:0007050; P:cell cycle arrest; ISS:AgBase.
GO; GO:0008219; P:cell death; ISS:AgBase.
GO; GO:0016477; P:cell migration; ISS:AgBase.
GO; GO:0000902; P:cell morphogenesis; ISS:AgBase.
GO; GO:0045216; P:cell-cell junction organization; ISS:AgBase.
GO; GO:0030199; P:collagen fibril organization; ISS:AgBase.
GO; GO:0048566; P:embryonic digestive tract development; ISS:AgBase.
GO; GO:0001837; P:epithelial to mesenchymal transition; ISS:AgBase.
GO; GO:0097191; P:extrinsic apoptotic signaling pathway; ISS:AgBase.
GO; GO:0001654; P:eye development; ISS:AgBase.
GO; GO:0008347; P:glial cell migration; ISS:AgBase.
GO; GO:0001942; P:hair follicle development; ISS:AgBase.
GO; GO:0007507; P:heart development; ISS:AgBase.
GO; GO:0003007; P:heart morphogenesis; ISS:AgBase.
GO; GO:0010693; P:negative regulation of alkaline phosphatase activity; ISS:AgBase.
GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
GO; GO:0030308; P:negative regulation of cell growth; ISS:AgBase.
GO; GO:0008285; P:negative regulation of cell proliferation; ISS:AgBase.
GO; GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:AgBase.
GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
GO; GO:0010936; P:negative regulation of macrophage cytokine production; ISS:AgBase.
GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; ISS:AgBase.
GO; GO:0051891; P:positive regulation of cardioblast differentiation; ISS:AgBase.
GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; ISS:AgBase.
GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-UniRule.
GO; GO:0030307; P:positive regulation of cell growth; ISS:AgBase.
GO; GO:0008284; P:positive regulation of cell proliferation; ISS:AgBase.
GO; GO:0010634; P:positive regulation of epithelial cell migration; ISS:AgBase.
GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; ISS:AgBase.
GO; GO:0045823; P:positive regulation of heart contraction; ISS:AgBase.
GO; GO:0045726; P:positive regulation of integrin biosynthetic process; ISS:AgBase.
GO; GO:0043525; P:positive regulation of neuron apoptotic process; ISS:AgBase.
GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
GO; GO:0045778; P:positive regulation of ossification; ISS:AgBase.
GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; ISS:AgBase.
GO; GO:1902895; P:positive regulation of pri-miRNA transcription by RNA polymerase II; IEA:Ensembl.
GO; GO:0050714; P:positive regulation of protein secretion; ISS:AgBase.
GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; ISS:AgBase.
GO; GO:0051795; P:positive regulation of timing of catagen; ISS:AgBase.
GO; GO:0006468; P:protein phosphorylation; ISS:AgBase.
GO; GO:0032909; P:regulation of transforming growth factor beta2 production; ISS:AgBase.
GO; GO:0042493; P:response to drug; ISS:AgBase.
GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
GO; GO:0032570; P:response to progesterone; ISS:AgBase.
GO; GO:0009611; P:response to wounding; ISS:AgBase.
GO; GO:0007435; P:salivary gland morphogenesis; ISS:AgBase.
GO; GO:0023014; P:signal transduction by protein phosphorylation; ISS:AgBase.
GO; GO:0060395; P:SMAD protein signal transduction; ISS:BHF-UCL.
GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:AgBase.
Gene3D; 2.10.90.10; -; 1.
InterPro; IPR029034; Cystine-knot_cytokine.
InterPro; IPR001839; TGF-b_C.
InterPro; IPR001111; TGF-b_propeptide.
InterPro; IPR016319; TGF-beta.
InterPro; IPR015615; TGF-beta-rel.
InterPro; IPR003940; TGFb2.
InterPro; IPR017948; TGFb_CS.
PANTHER; PTHR11848; PTHR11848; 1.
PANTHER; PTHR11848:SF141; PTHR11848:SF141; 1.
Pfam; PF00019; TGF_beta; 1.
Pfam; PF00688; TGFb_propeptide; 1.
PIRSF; PIRSF001787; TGF-beta; 1.
PRINTS; PR01423; TGFBETA.
PRINTS; PR01425; TGFBETA2.
SMART; SM00204; TGFB; 1.
SUPFAM; SSF57501; SSF57501; 1.
PROSITE; PS00250; TGF_BETA_1; 1.
PROSITE; PS51362; TGF_BETA_2; 1.
3: Inferred from homology;
Complete proteome {ECO:0000313|Proteomes:UP000009130};
Disulfide bond {ECO:0000256|SAAS:SAAS00516088};
Growth factor {ECO:0000256|PIRNR:PIRNR001787,
ECO:0000256|RuleBase:RU000354, ECO:0000256|SAAS:SAAS00516085};
Mitogen {ECO:0000256|PIRNR:PIRNR001787};
Reference proteome {ECO:0000313|Proteomes:UP000009130};
Secreted {ECO:0000256|PIRNR:PIRNR001787,
ECO:0000256|SAAS:SAAS00516087};
Signal {ECO:0000256|PIRNR:PIRNR001787}.
SIGNAL 1 20 {ECO:0000256|PIRNR:PIRNR001787}.
CHAIN 21 442 Transforming growth factor beta.
{ECO:0000256|PIRNR:PIRNR001787}.
/FTId=PRO_5014303875.
DOMAIN 327 442 TGF_BETA_2.
{ECO:0000259|PROSITE:PS51362}.
SEQUENCE 442 AA; 50573 MW; 5D7A3C2ED51753D5 CRC64;
MHYCVLSAFL ILHLVTVALS LSTCSTLDMD QFMRKRIEAI RGQILSKLKL TSPPEDYPEP
EEVPPEVISI YNSTRDLLQE KASRRAAACE RERSDEEYYA KEVYKIDMPP FFPSETVCPV
VTTPSGSVGS LCSRQSQVLC GYLDAIPPTF YRPYFRIVRF DVSAMEKNAS NLVKAEFRVF
RLQNPKARVP EQRIELYQIL KSKDLTSPTQ RYIDSKVVKT RAEGEWLSFD VTDAVHEWLH
HKDRNLGFKI SLHCPCCTFV PSNNYIIPNK SEELEARFAG IDGTSTYTSG DQKTIKSTRK
KNSGKTPHLL LMLLPSYRLE SQQTNRRKKR ALDAAYCFRN VQDNCCLRPL YIDFKRDLGW
KWIHEPKGYN ANFCAGACPY LWSSDTQHSR VLSLYNTINP EASASPCCVS QDLEPLTILY
YIGKTPKIEQ LSNMIVKSCK CS


Related products :

Catalog number Product name Quantity
EIAAB08798 C16orf11,Homo sapiens,Human,Uncharacterized protein C16orf11,Uncharacterized protein RJD1
EIAAB10060 CXorf52,Homo sapiens,Human,LINC00204A,NCRNA00204,Putative uncharacterized protein CXorf52,Putative uncharacterized protein encoded by LINC00204A,SPCX
18-003-44116 Putative uncharacterized protein - Putative uncharacterized protein LOC55565; LOC55565 protein Polyclonal 0.05 mg Aff Pur
EIAAB06906 Emprin,Extracellular matrix protein with prion homology,Mouse,Mus musculus,Protein STG,Stg,Uncharacterized protein C6orf15 homolog
EIAAB07568 Ag2,Protein Ag2,Rat,Rattus norvegicus,Uncharacterized protein C11orf96 homolog
EIAAB07548 Mouse,Mus musculus,Nwc,Protein NWC,Uncharacterized protein C11orf74 homolog
EIAAB06945 Nod3l,NOD3-like protein,Rat,Rattus norvegicus,Uncharacterized protein C6orf154 homolog
EIAAB06257 Mouse,Mus musculus,Osap,Ovary-specific acidic protein,Uncharacterized protein C4orf49 homolog
EIAAB07500 Mouse,Mus musculus,Oocyte-testis gene 1 protein,Otg1,Uncharacterized protein C10orf118 homolog
EIAAB06256 Bos taurus,Bovine,OSAP,Ovary-specific acidic protein,Uncharacterized protein C4orf49 homolog
EIAAB10025 Mouse,Mus musculus,Testis-specific expressed protein 2,TSEG2,TSEG-2,Uncharacterized protein C22orf41 homolog
EIAAB07459 Kiaa2006,Mouse,Mus musculus,Pap20,Peripheral benzodiazepine receptor-associated protein 20,Uncharacterized protein C10orf18 homolog
EIAAB07546 L7rn6,Lethal gene on chromosome 7 Rinchik 6 protein,Mouse,Mus musculus,Uncharacterized protein C11orf73 homolog
EIAAB07317 Mouse,Mus musculus,Smrp1,Spermatid-specific manchette-related protein 1,Uncharacterized protein C9orf24 homolog
EIAAB08112 C14orf162,Homo sapiens,Human,Myelin proteolipid protein-like protein,PLPL,Uncharacterized protein C14orf162
EIAAB07067 C8orf42,Homo sapiens,Human,Protein INM01,Protein TDRP,Uncharacterized protein C8orf42
20-783-73159 MOUSE ANTI HUMAN C1q - C1q and tumor necrosis factor related protein 5. isoform CRA_a; Uncharacterized protein C1QTNF5 Monoclonal 0.1 mg
EIAAB06227 C4orf3,HCV F-transactivated protein 1,Hepatitis C virus F protein-transactivated protein 1,Homo sapiens,Human,Uncharacterized protein C4orf3
18-003-44281 Putative uncharacterized protein - N_A Polyclonal 0.1 mg Protein A
18-003-44025 Uncharacterized protein KIAA1849 - N_A Polyclonal 0.1 mg Protein A
18-003-43635 Putative uncharacterized protein - N_A Polyclonal 0.1 mg Protein A
18-003-43838 Putative uncharacterized protein - N_A Polyclonal 0.1 mg Protein A
EH1144 Uncharacterized protein C13orf33 Elisa Kit 96T
EH1184 Uncharacterized protein KIAA1377 Elisa Kit 96T
18-003-42509 Uncharacterized protein C14orf101 - N_A Polyclonal 0.05 mg Aff Pur


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: +49 0241 40 08 90 86, +49 0241 95 78 94 78, +49 0241 40 08 90 86
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur