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Utx protein (Fragment)

 Q8R2W5_MOUSE            Unreviewed;       996 AA.
Q8R2W5;
01-JUN-2002, integrated into UniProtKB/TrEMBL.
01-JUN-2002, sequence version 1.
05-JUL-2017, entry version 70.
SubName: Full=Utx protein {ECO:0000313|EMBL:AAH27130.1};
Flags: Fragment;
Name=Kdm6a {ECO:0000313|MGI:MGI:1095419};
Synonyms=Utx {ECO:0000313|EMBL:AAH27130.1};
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH27130.1};
[1] {ECO:0000313|EMBL:AAH27130.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=FVB/N {ECO:0000313|EMBL:AAH27130.1};
TISSUE=Mammary tumor. C3 {ECO:0000313|EMBL:AAH27130.1};
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M.,
Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S.,
Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F.,
Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J.,
Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N.,
Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B.,
Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B.,
Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S.,
Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R.,
Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L.,
Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E.,
Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D.,
Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G.,
Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J.,
Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L.,
Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D.,
Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A.,
Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S.,
Makowski K.A., Bosak S., Malek J.;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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EMBL; BC027130; AAH27130.1; -; mRNA.
UniGene; Mm.257498; -.
UniGene; Mm.417709; -.
ProteinModelPortal; Q8R2W5; -.
PaxDb; Q8R2W5; -.
PeptideAtlas; Q8R2W5; -.
MGI; MGI:1095419; Kdm6a.
eggNOG; KOG1124; Eukaryota.
eggNOG; KOG1246; Eukaryota.
eggNOG; COG0457; LUCA.
HOVERGEN; HBG018063; -.
ChiTaRS; Kdm6a; mouse.
GO; GO:0071558; F:histone demethylase activity (H3-K27 specific); IEA:InterPro.
GO; GO:0046872; F:metal ion binding; IEA:InterPro.
GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
InterPro; IPR003347; JmjC_dom.
InterPro; IPR029516; KDM6C.
PANTHER; PTHR14017:SF19; PTHR14017:SF19; 1.
Pfam; PF02373; JmjC; 1.
SMART; SM00558; JmjC; 1.
PROSITE; PS51184; JMJC; 1.
2: Evidence at transcript level;
DOMAIN 690 853 JmjC. {ECO:0000259|PROSITE:PS51184}.
NON_TER 1 1 {ECO:0000313|EMBL:AAH27130.1}.
SEQUENCE 996 AA; 109061 MW; A6991092439B7614 CRC64;
GTLYESCNQP QDAIKCYLNA TRSKNCSNTS GLAARIKYLQ NTSDNWSGGN APPPVEQQTH
SWCLTPQKLQ HLEQLRANRN NLNPAQKLML EQLESQFVLM QQHQMRQTGV AQVRPTGILN
GPTVDSSLPT NSVSGQQPQL PLTRMPSVSQ PGVHTACPRQ TLANGPFSAG HVPCSTSRTL
GSTDTVLIGN NHVTGSGSNG NVPYLQRNAP TLPHNRTNLT SSTEEPWKNQ LSNSTQGLHK
GPSSHLAGPN GERPLSSTGP SQHLQAAGSG IQNQNGHPTL PSNSVTQGAA LNHLSSHTAT
SGGQQGITLT KESKPSGNTL TVPETSRQTG ETPNSTASVE GLPNHVHQVM ADAVCSPSHG
DSKSPGLLSS DNPQLSALLM GKANNNVGPG TCDKVNNIHP TVHTKTDNSV ASSPSSAIST
ATPSPKSTEQ TTTNSVTSLN SPHSGLHTIN GEGMEESQSP IKTDLLLVSH RPSPQIIPSM
SVSIYPSSAE VLKACRNLGK NGLSNSSILL DKCPPPRPPS SPYPPLPKDK LNPPTPSIYL
ENKRDAFFPP LHQFCTNPNN PVTVIRGLAG ALKLDLGLFS TKTLVEANNE HMVEVRTQLL
QPADENWDPT GTKKIWHCES NRSHTTIAKY AQYQASSFQE SLREENEKRS HHKDHSDSES
TSSDNSGKRR KGPFKTIKFG TNIDLSDDKK WKLQLHELTK LPAFVRVVSA GNLLSHVGHT
ILGMNTVQLY MKVPGSRTPG HQENNNFCSV NINIGPGDCE WFVVPEGYWG VLNDFCEKNN
LNFLMGSWWP NLEDLYEANV PVYRFIQRPG DLVWINAGTV HWVQAIGWCN NIAWNVGPLT
ACQYKLAVER YEWNKLQNVK SIVPMVHLSW NMARNIKVSD PKLFEMIKYC LLRTLKQCQT
LREALIAAGK EIIWHGRTKE EPAHYCSICE GEVFDLLFVT NESNSRKTYI VHCQDCARKT
SGNLENFVVL EQYKMEDLMQ VYDQFTLAPP LPSASS


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