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Virion infectivity factor (Vif) (SOR protein) [Cleaved into: p17; p7]

 A0A1L7DWZ5_9HIV1        Unreviewed;       192 AA.
15-MAR-2017, integrated into UniProtKB/TrEMBL.
15-MAR-2017, sequence version 1.
18-JUL-2018, entry version 11.
RecName: Full=Virion infectivity factor {ECO:0000256|RuleBase:RU003341};
Name=vif {ECO:0000313|EMBL:APU04807.1};
Human immunodeficiency virus 1.
Viruses; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
NCBI_TaxID=11676 {ECO:0000313|EMBL:APU04807.1};
NCBI_TaxID=9606; Homo sapiens (Human).
[1] {ECO:0000313|EMBL:APU04807.1}
STRAIN=CH427.PL.011608.A2.1 {ECO:0000313|EMBL:APU04152.1},
CH427.PL.011608.A2.10 {ECO:0000313|EMBL:APU04161.1},
CH427.PL.011608.A2.2 {ECO:0000313|EMBL:APU04170.1},
CH427.PL.011608.A2.3 {ECO:0000313|EMBL:APU04179.1},
CH427.PL.011608.A2.4 {ECO:0000313|EMBL:APU04188.1},
CH427.PL.011608.A2.5 {ECO:0000313|EMBL:APU04197.1},
CH427.PL.011608.A2.6 {ECO:0000313|EMBL:APU04206.1},
CH427.PL.011608.A2.7 {ECO:0000313|EMBL:APU04215.1},
CH427.PL.011608.A2.8 {ECO:0000313|EMBL:APU04224.1},
CH427.PL.011608.A2.9 {ECO:0000313|EMBL:APU04233.1},
CH427.PL.011608.BE.1 {ECO:0000313|EMBL:APU04242.1},
CH427.PL.011608.UT.1 {ECO:0000313|EMBL:APU04251.1},
CH427.PL.011608.UT.10 {ECO:0000313|EMBL:APU04260.1},
CH427.PL.011608.UT.2 {ECO:0000313|EMBL:APU04269.1},
CH427.PL.011608.UT.3 {ECO:0000313|EMBL:APU04278.1},
CH427.PL.011608.UT.4 {ECO:0000313|EMBL:APU04287.1},
CH427.PL.011608.UT.5 {ECO:0000313|EMBL:APU04296.1},
CH427.PL.011608.UT.6 {ECO:0000313|EMBL:APU04304.1},
CH427.PL.011608.UT.7 {ECO:0000313|EMBL:APU04313.1},
CH427.PL.011608.UT.8 {ECO:0000313|EMBL:APU04322.1},
CH427.PL.011608.UT.9 {ECO:0000313|EMBL:APU04331.1},
CH427_SGA.600.1 {ECO:0000313|EMBL:APU07260.1},
CH427_SGA.600.11 {ECO:0000313|EMBL:APU07275.1},
CH427_SGA.600.12 {ECO:0000313|EMBL:APU07283.1},
CH427_SGA.600.13 {ECO:0000313|EMBL:APU07290.1},
CH427_SGA.600.14 {ECO:0000313|EMBL:APU07298.1},
CH427_SGA.600.15 {ECO:0000313|EMBL:APU07306.1},
CH427_SGA.600.16 {ECO:0000313|EMBL:APU07314.1},
CH427_SGA.600.18 {ECO:0000313|EMBL:APU07322.1},
CH427_SGA.600.19 {ECO:0000313|EMBL:APU07330.1},
CH427_SGA.600.2 {ECO:0000313|EMBL:APU07338.1},
CH427_SGA.600.20 {ECO:0000313|EMBL:APU07346.1},
CH427_SGA.600.21 {ECO:0000313|EMBL:APU07354.1},
CH427_SGA.600.24 {ECO:0000313|EMBL:APU07369.1},
CH427_SGA.600.25 {ECO:0000313|EMBL:APU07377.1},
CH427_SGA.600.26 {ECO:0000313|EMBL:APU07385.1},
CH427_SGA.600.27 {ECO:0000313|EMBL:APU07393.1},
CH427_SGA.600.29 {ECO:0000313|EMBL:APU07401.1},
CH427_SGA.600.30 {ECO:0000313|EMBL:APU07416.1},
CH427_SGA.600.31 {ECO:0000313|EMBL:APU07424.1},
CH427_SGA.600.32 {ECO:0000313|EMBL:APU07432.1},
CH427_SGA.600.33 {ECO:0000313|EMBL:APU07440.1},
CH427_SGA.600.35 {ECO:0000313|EMBL:APU07448.1},
CH427_SGA.600.36 {ECO:0000313|EMBL:APU07456.1},
CH427_SGA.600.37 {ECO:0000313|EMBL:APU07464.1},
CH427_SGA.600.39 {ECO:0000313|EMBL:APU07472.1},
CH427_SGA.600.4 {ECO:0000313|EMBL:APU07479.1},
CH427_SGA.600.6 {ECO:0000313|EMBL:APU07487.1},
CH427_SGA.600.7 {ECO:0000313|EMBL:APU07495.1},
CH427_SGA.600.8 {ECO:0000313|EMBL:APU07503.1},
CH427_SGA.600.9 {ECO:0000313|EMBL:APU07511.1},
CH492.CV.020608.UT.10 {ECO:0000313|EMBL:APU04421.1},
CH492.CV.020608.UT.11 {ECO:0000313|EMBL:APU04430.1},
CH492.CV.020608.UT.16 {ECO:0000313|EMBL:APU04475.1},
CH492.CV.020608.UT.17 {ECO:0000313|EMBL:APU04484.1},
CH492.CV.020608.UT.3 {ECO:0000313|EMBL:APU04502.1},
CH492.CV.020608.UT.5 {ECO:0000313|EMBL:APU04520.1},
CH492.CV.020608.UT.6 {ECO:0000313|EMBL:APU04529.1},
CH492.CV.020608.UT.7 {ECO:0000313|EMBL:APU04538.1},
CH492.CV.020608.UT.9 {ECO:0000313|EMBL:APU04556.1},
CH492.PL.031108.A2.10 {ECO:0000313|EMBL:APU04574.1},
CH492.PL.031108.A2.11 {ECO:0000313|EMBL:APU04583.1},
CH492.PL.031108.A2.12 {ECO:0000313|EMBL:APU04592.1},
CH492.PL.031108.A2.13 {ECO:0000313|EMBL:APU04601.1},
CH492.PL.031108.A2.15 {ECO:0000313|EMBL:APU04619.1},
CH492.PL.031108.A2.16 {ECO:0000313|EMBL:APU04628.1},
CH492.PL.031108.A2.3 {ECO:0000313|EMBL:APU04673.1},
CH492.PL.031108.A2.4 {ECO:0000313|EMBL:APU04682.1},
CH492.PL.031108.A2.5 {ECO:0000313|EMBL:APU04691.1},
CH492.PL.031108.BE.11 {ECO:0000313|EMBL:APU04753.1},
CH492.PL.031108.BE.12 {ECO:0000313|EMBL:APU04762.1},
CH492.PL.031108.BE.14 {ECO:0000313|EMBL:APU04780.1},
CH492.PL.031108.BE.2 {ECO:0000313|EMBL:APU04789.1},
CH492.PL.031108.BE.4 {ECO:0000313|EMBL:APU04807.1},
CH492.PL.031108.BE.5 {ECO:0000313|EMBL:APU04816.1},
CH492.PL.031108.BE.7 {ECO:0000313|EMBL:APU04834.1},
CH492.PL.031108.BE.8 {ECO:0000313|EMBL:APU04843.1},
CH492.PL.031108.BE.9 {ECO:0000313|EMBL:APU04852.1},
CH492.PL.031108.UT.12 {ECO:0000313|EMBL:APU04888.1},
CH492.PL.031108.UT.13 {ECO:0000313|EMBL:APU04897.1},
CH492.PL.031108.UT.2 {ECO:0000313|EMBL:APU04906.1},
CH492.PL.031108.UT.3 {ECO:0000313|EMBL:APU04915.1},
CH492.PL.031108.UT.4 {ECO:0000313|EMBL:APU04924.1},
CH492.PL.031108.UT.6 {ECO:0000313|EMBL:APU04942.1},
CH492.PL.031108.UT.7 {ECO:0000313|EMBL:APU04951.1},
CH492.PL.031108.UT.9 {ECO:0000313|EMBL:APU04969.1},
CH492_SGA.1A5 {ECO:0000313|EMBL:APU07526.1},
CH492_SGA.1A7 {ECO:0000313|EMBL:APU07534.1},
CH492_SGA.1A8 {ECO:0000313|EMBL:APU07541.1},
CH492_SGA.1A9 {ECO:0000313|EMBL:APU07549.1},
CH492_SGA.1B11 {ECO:0000313|EMBL:APU07557.1},
CH492_SGA.1B5 {ECO:0000313|EMBL:APU07565.1},
CH492_SGA.1D12 {ECO:0000313|EMBL:APU07573.1},
CH492_SGA.1D3 {ECO:0000313|EMBL:APU07589.1},
CH492_SGA.1D4 {ECO:0000313|EMBL:APU07597.1},
CH492_SGA.1D6 {ECO:0000313|EMBL:APU07605.1},
CH492_SGA.1E1 {ECO:0000313|EMBL:APU07613.1},
CH492_SGA.1F11 {ECO:0000313|EMBL:APU07645.1},
CH492_SGA.1G3 {ECO:0000313|EMBL:APU07661.1},
CH492_SGA.1H1 {ECO:0000313|EMBL:APU07669.1},
CH492_SGA.1H11 {ECO:0000313|EMBL:APU07677.1},
CH492_SGA.1H8 {ECO:0000313|EMBL:APU07692.1},
CH492_SGA.2B7 {ECO:0000313|EMBL:APU07708.1},
CH492_SGA.2B8 {ECO:0000313|EMBL:APU07716.1},
CH492_SGA.2C12 {ECO:0000313|EMBL:APU07724.1},
CH492_SGA.2E7 {ECO:0000313|EMBL:APU07748.1},
CH492_SGA.2F5 {ECO:0000313|EMBL:APU07756.1},
CH492_SGA.2G12 {ECO:0000313|EMBL:APU07771.1},
CH492_SGA.2G4 {ECO:0000313|EMBL:APU07787.1},
CH492_SGA.2G6 {ECO:0000313|EMBL:APU07795.1},
CH492_SGA.2G8 {ECO:0000313|EMBL:APU07803.1}, and
CH492_SGA.2H8 {ECO:0000313|EMBL:APU07811.1};
Iyer S.S., Bibollet-Ruche F., Sherrill-Mix S., Learn G.H.,
Plenderleith L., Smith A.G., Barbian H.J., Russell R.M., Gondim M.V.,
Bahari C.Y., Shaw C.M., Li Y., Decker T., Haynes B.F., Shaw G.M.,
Sharp P.M., Borrow P., Hahn B.H.;
"Resistance to type 1 interferons is a major determinant of HIV-1
transmission fitness.";
Proc. Natl. Acad. Sci. U.S.A. 0:0-0(2017).
-!- SUBCELLULAR LOCATION: Host cell membrane
{ECO:0000256|RuleBase:RU003341, ECO:0000256|SAAS:SAAS01059686};
Peripheral membrane protein {ECO:0000256|RuleBase:RU003341,
ECO:0000256|SAAS:SAAS01059686}; Cytoplasmic side
{ECO:0000256|RuleBase:RU003341, ECO:0000256|SAAS:SAAS01059686}.
Host cytoplasm {ECO:0000256|RuleBase:RU003341}. Virion
{ECO:0000256|RuleBase:RU003341, ECO:0000256|SAAS:SAAS01059682}.
Note=In the cytoplasm, seems to colocalize with intermediate
filament vimentin. A fraction is associated with the cytoplasmic
side of cellular membranes, presumably via the interaction with
Pr55Gag precursor. {ECO:0000256|RuleBase:RU003341}.
-!- SIMILARITY: Belongs to the primate lentivirus group Vif protein
family. {ECO:0000256|RuleBase:RU003341,
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
EMBL; KY112197; APU04152.1; -; Genomic_RNA.
EMBL; KY112198; APU04161.1; -; Genomic_RNA.
EMBL; KY112199; APU04170.1; -; Genomic_RNA.
EMBL; KY112200; APU04179.1; -; Genomic_RNA.
EMBL; KY112201; APU04188.1; -; Genomic_RNA.
EMBL; KY112202; APU04197.1; -; Genomic_RNA.
EMBL; KY112203; APU04206.1; -; Genomic_RNA.
EMBL; KY112204; APU04215.1; -; Genomic_RNA.
EMBL; KY112205; APU04224.1; -; Genomic_RNA.
EMBL; KY112206; APU04233.1; -; Genomic_RNA.
EMBL; KY112207; APU04242.1; -; Genomic_RNA.
EMBL; KY112208; APU04251.1; -; Genomic_RNA.
EMBL; KY112209; APU04260.1; -; Genomic_RNA.
EMBL; KY112210; APU04269.1; -; Genomic_RNA.
EMBL; KY112211; APU04278.1; -; Genomic_RNA.
EMBL; KY112212; APU04287.1; -; Genomic_RNA.
EMBL; KY112213; APU04296.1; -; Genomic_RNA.
EMBL; KY112214; APU04304.1; -; Genomic_RNA.
EMBL; KY112215; APU04313.1; -; Genomic_RNA.
EMBL; KY112216; APU04322.1; -; Genomic_RNA.
EMBL; KY112217; APU04331.1; -; Genomic_RNA.
EMBL; KY112260; APU04421.1; -; Genomic_RNA.
EMBL; KY112261; APU04430.1; -; Genomic_RNA.
EMBL; KY112266; APU04475.1; -; Genomic_RNA.
EMBL; KY112267; APU04484.1; -; Genomic_RNA.
EMBL; KY112269; APU04502.1; -; Genomic_RNA.
EMBL; KY112271; APU04520.1; -; Genomic_RNA.
EMBL; KY112272; APU04529.1; -; Genomic_RNA.
EMBL; KY112273; APU04538.1; -; Genomic_RNA.
EMBL; KY112275; APU04556.1; -; Genomic_RNA.
EMBL; KY112277; APU04574.1; -; Genomic_RNA.
EMBL; KY112278; APU04583.1; -; Genomic_RNA.
EMBL; KY112279; APU04592.1; -; Genomic_RNA.
EMBL; KY112280; APU04601.1; -; Genomic_RNA.
EMBL; KY112282; APU04619.1; -; Genomic_RNA.
EMBL; KY112283; APU04628.1; -; Genomic_RNA.
EMBL; KY112288; APU04673.1; -; Genomic_RNA.
EMBL; KY112289; APU04682.1; -; Genomic_RNA.
EMBL; KY112290; APU04691.1; -; Genomic_RNA.
EMBL; KY112297; APU04753.1; -; Genomic_RNA.
EMBL; KY112298; APU04762.1; -; Genomic_RNA.
EMBL; KY112300; APU04780.1; -; Genomic_RNA.
EMBL; KY112301; APU04789.1; -; Genomic_RNA.
EMBL; KY112303; APU04807.1; -; Genomic_RNA.
EMBL; KY112304; APU04816.1; -; Genomic_RNA.
EMBL; KY112306; APU04834.1; -; Genomic_RNA.
EMBL; KY112307; APU04843.1; -; Genomic_RNA.
EMBL; KY112308; APU04852.1; -; Genomic_RNA.
EMBL; KY112312; APU04888.1; -; Genomic_RNA.
EMBL; KY112313; APU04897.1; -; Genomic_RNA.
EMBL; KY112314; APU04906.1; -; Genomic_RNA.
EMBL; KY112315; APU04915.1; -; Genomic_RNA.
EMBL; KY112316; APU04924.1; -; Genomic_RNA.
EMBL; KY112318; APU04942.1; -; Genomic_RNA.
EMBL; KY112319; APU04951.1; -; Genomic_RNA.
EMBL; KY112321; APU04969.1; -; Genomic_RNA.
EMBL; KY112218; APU07260.1; -; Genomic_RNA.
EMBL; KY112220; APU07275.1; -; Genomic_RNA.
EMBL; KY112221; APU07283.1; -; Genomic_RNA.
EMBL; KY112222; APU07290.1; -; Genomic_RNA.
EMBL; KY112223; APU07298.1; -; Genomic_RNA.
EMBL; KY112224; APU07306.1; -; Genomic_RNA.
EMBL; KY112225; APU07314.1; -; Genomic_RNA.
EMBL; KY112226; APU07322.1; -; Genomic_RNA.
EMBL; KY112227; APU07330.1; -; Genomic_RNA.
EMBL; KY112228; APU07338.1; -; Genomic_RNA.
EMBL; KY112229; APU07346.1; -; Genomic_RNA.
EMBL; KY112230; APU07354.1; -; Genomic_RNA.
EMBL; KY112232; APU07369.1; -; Genomic_RNA.
EMBL; KY112233; APU07377.1; -; Genomic_RNA.
EMBL; KY112234; APU07385.1; -; Genomic_RNA.
EMBL; KY112235; APU07393.1; -; Genomic_RNA.
EMBL; KY112236; APU07401.1; -; Genomic_RNA.
EMBL; KY112238; APU07416.1; -; Genomic_RNA.
EMBL; KY112239; APU07424.1; -; Genomic_RNA.
EMBL; KY112240; APU07432.1; -; Genomic_RNA.
EMBL; KY112241; APU07440.1; -; Genomic_RNA.
EMBL; KY112242; APU07448.1; -; Genomic_RNA.
EMBL; KY112243; APU07456.1; -; Genomic_RNA.
EMBL; KY112244; APU07464.1; -; Genomic_RNA.
EMBL; KY112245; APU07472.1; -; Genomic_RNA.
EMBL; KY112246; APU07479.1; -; Genomic_RNA.
EMBL; KY112247; APU07487.1; -; Genomic_RNA.
EMBL; KY112248; APU07495.1; -; Genomic_RNA.
EMBL; KY112249; APU07503.1; -; Genomic_RNA.
EMBL; KY112250; APU07511.1; -; Genomic_RNA.
EMBL; KY112323; APU07526.1; -; Genomic_RNA.
EMBL; KY112324; APU07534.1; -; Genomic_RNA.
EMBL; KY112325; APU07541.1; -; Genomic_RNA.
EMBL; KY112326; APU07549.1; -; Genomic_RNA.
EMBL; KY112327; APU07557.1; -; Genomic_RNA.
EMBL; KY112328; APU07565.1; -; Genomic_RNA.
EMBL; KY112329; APU07573.1; -; Genomic_RNA.
EMBL; KY112331; APU07589.1; -; Genomic_RNA.
EMBL; KY112332; APU07597.1; -; Genomic_RNA.
EMBL; KY112333; APU07605.1; -; Genomic_RNA.
EMBL; KY112334; APU07613.1; -; Genomic_RNA.
EMBL; KY112338; APU07645.1; -; Genomic_RNA.
EMBL; KY112340; APU07661.1; -; Genomic_RNA.
EMBL; KY112341; APU07669.1; -; Genomic_RNA.
EMBL; KY112342; APU07677.1; -; Genomic_RNA.
EMBL; KY112344; APU07692.1; -; Genomic_RNA.
EMBL; KY112346; APU07708.1; -; Genomic_RNA.
EMBL; KY112347; APU07716.1; -; Genomic_RNA.
EMBL; KY112348; APU07724.1; -; Genomic_RNA.
EMBL; KY112351; APU07748.1; -; Genomic_RNA.
EMBL; KY112352; APU07756.1; -; Genomic_RNA.
EMBL; KY112354; APU07771.1; -; Genomic_RNA.
EMBL; KY112356; APU07787.1; -; Genomic_RNA.
EMBL; KY112357; APU07795.1; -; Genomic_RNA.
EMBL; KY112358; APU07803.1; -; Genomic_RNA.
EMBL; KY112359; APU07811.1; -; Genomic_RNA.
GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
GO; GO:0019012; C:virion; IEA:UniProtKB-SubCell.
GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
GO; GO:0019058; P:viral life cycle; IEA:InterPro.
HAMAP; MF_04081; HIV_VIF; 1.
InterPro; IPR000475; Viral_infect.
Pfam; PF00559; Vif; 1.
3: Inferred from homology;
Host cell membrane {ECO:0000256|SAAS:SAAS01059755};
Host cytoplasm {ECO:0000256|SAAS:SAAS01059745};
Host membrane {ECO:0000256|SAAS:SAAS01059755};
Host-virus interaction {ECO:0000256|SAAS:SAAS01059733};
Membrane {ECO:0000256|SAAS:SAAS01059755};
Ubl conjugation pathway {ECO:0000256|SAAS:SAAS01059744};
Virion {ECO:0000256|SAAS:SAAS01059762}.
SEQUENCE 192 AA; 22748 MW; 6FD173D1D4C07469 CRC64;

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'L0234-1 Complement factor B (cleaved) antibody Ab host: Rabbit 50 Вµg
'L0234-2 Complement factor B (cleaved) antibody Ab host: Rabbit 0.1 mg
L0204-1 Coagulation factor XII (F12) (cleaved) Rabbit antibody Ab Aff - Purified 50
'L0204-2 Coagulation factor XII (F12) (cleaved) antibody Ab host: Rabbit 0.1 mg
'L0204-1 Coagulation factor XII (F12) (cleaved) antibody Ab host: Rabbit 50 Вµg
'L0203-1 Coagulation factor XII (F12) (cleaved) antibody Ab host: Rabbit 50 Вµg
'L0199-2 Coagulation factor X (F10) (cleaved) antibody Ab host: Rabbit 0.1 mg
'L0199-1 Coagulation factor X (F10) (cleaved) antibody Ab host: Rabbit 50 Вµg
'L0126-2 Coagulation factor X (F10) (cleaved) antibody Ab host: Rabbit 0.1 mg
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