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WASH complex subunit 1

 F1NMK3_CHICK            Unreviewed;       476 AA.
F1NMK3;
03-MAY-2011, integrated into UniProtKB/TrEMBL.
03-MAY-2011, sequence version 1.
20-JUN-2018, entry version 49.
SubName: Full=WASH complex subunit 1 {ECO:0000313|Ensembl:ENSGALP00000029912};
Name=WASHC1 {ECO:0000313|Ensembl:ENSGALP00000029912};
Gallus gallus (Chicken).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
Phasianidae; Phasianinae; Gallus.
NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00000029912, ECO:0000313|Proteomes:UP000000539};
[1] {ECO:0000313|Ensembl:ENSGALP00000029912, ECO:0000313|Proteomes:UP000000539}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000029912,
ECO:0000313|Proteomes:UP000000539};
PubMed=15592404; DOI=10.1038/nature03154;
International Chicken Genome Sequencing Consortium;
Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C.,
Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E.,
Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W.,
Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A., Kremitzki C.,
Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E.,
Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J.,
Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M.,
Paton B., Smith J., Morrice D., Daniels L., Tempest H.G.,
Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V.,
Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J.,
van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J.,
Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H.,
Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K.,
Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E.,
Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M.,
Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S.,
Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J.,
Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H.,
Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C.,
Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C.,
Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P.,
King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S.,
Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S.,
Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S.,
Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z.,
Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J.,
Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z.,
Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M.,
Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O.,
Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J.,
Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G.,
Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D.,
Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G.,
Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A.,
Mardis E.R., Wilson R.K.;
"Sequence and comparative analysis of the chicken genome provide
unique perspectives on vertebrate evolution.";
Nature 432:695-716(2004).
[2] {ECO:0000313|Ensembl:ENSGALP00000029912}
IDENTIFICATION.
STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000029912};
Ensembl;
Submitted (JUL-2011) to UniProtKB.
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EMBL; AC174384; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; XP_015141229.1; XM_015285743.1.
RefSeq; XP_015141238.1; XM_015285752.1.
UniGene; Gga.8315; -.
Ensembl; ENSGALT00000030549; ENSGALP00000029912; ENSGALG00000012974.
GeneID; 418145; -.
CTD; 100287171; -.
eggNOG; ENOG410IFZ4; Eukaryota.
eggNOG; ENOG410YN2V; LUCA.
GeneTree; ENSGT00390000016717; -.
OMA; NLRHEET; -.
OrthoDB; EOG091G0GKX; -.
PhylomeDB; F1NMK3; -.
TreeFam; TF318222; -.
Proteomes; UP000000539; Chromosome 1.
Bgee; ENSGALG00000012974; -.
GO; GO:0005776; C:autophagosome; IEA:Ensembl.
GO; GO:0031083; C:BLOC-1 complex; IEA:Ensembl.
GO; GO:0005813; C:centrosome; IEA:Ensembl.
GO; GO:0005769; C:early endosome; IEA:Ensembl.
GO; GO:0000145; C:exocyst; IEA:Ensembl.
GO; GO:0071437; C:invadopodium; IEA:Ensembl.
GO; GO:0055037; C:recycling endosome; IEA:Ensembl.
GO; GO:0071203; C:WASH complex; IEA:Ensembl.
GO; GO:0003779; F:actin binding; IEA:InterPro.
GO; GO:0043014; F:alpha-tubulin binding; IEA:Ensembl.
GO; GO:0043015; F:gamma-tubulin binding; IEA:Ensembl.
GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl.
GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IEA:Ensembl.
GO; GO:0002468; P:dendritic cell antigen processing and presentation; IEA:Ensembl.
GO; GO:0007032; P:endosome organization; IEA:Ensembl.
GO; GO:0099638; P:endosome to plasma membrane protein transport; IEA:Ensembl.
GO; GO:0006887; P:exocytosis; IEA:Ensembl.
GO; GO:0022617; P:extracellular matrix disassembly; IEA:Ensembl.
GO; GO:0034383; P:low-density lipoprotein particle clearance; IEA:Ensembl.
GO; GO:0010507; P:negative regulation of autophagy; IEA:Ensembl.
GO; GO:0043553; P:negative regulation of phosphatidylinositol 3-kinase activity; IEA:Ensembl.
GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
GO; GO:0040038; P:polar body extrusion after meiotic divisions; IEA:Ensembl.
GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
GO; GO:1904109; P:positive regulation of cholesterol import; IEA:Ensembl.
GO; GO:2000010; P:positive regulation of protein localization to cell surface; IEA:Ensembl.
GO; GO:0031274; P:positive regulation of pseudopodium assembly; IEA:Ensembl.
GO; GO:0034394; P:protein localization to cell surface; IEA:Ensembl.
GO; GO:0050776; P:regulation of immune response; IEA:Ensembl.
GO; GO:0031396; P:regulation of protein ubiquitination; IEA:Ensembl.
GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:Ensembl.
GO; GO:0090306; P:spindle assembly involved in meiosis; IEA:Ensembl.
GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
InterPro; IPR028290; WASH1.
InterPro; IPR021854; WASH1_WAHD.
InterPro; IPR003124; WH2_dom.
PANTHER; PTHR23331; PTHR23331; 1.
Pfam; PF11945; WASH_WAHD; 1.
PROSITE; PS51082; WH2; 1.
4: Predicted;
Coiled coil {ECO:0000256|SAM:Coils};
Complete proteome {ECO:0000313|Proteomes:UP000000539};
Reference proteome {ECO:0000313|Proteomes:UP000000539}.
DOMAIN 366 388 WH2. {ECO:0000259|PROSITE:PS51082}.
COILED 382 402 {ECO:0000256|SAM:Coils}.
SEQUENCE 476 AA; 51652 MW; 17483836C08BE4E6 CRC64;
MTTVAQNHFL EGQTYSVPLI QPDLRREEAV QQVADALQYL QKVSGDIFNR ISQRVETSRA
QLQAISERVT LAQAKIEKIK GSKKAIKVFS SAKYPAPERL QEYCSIFAGA EDPAKQKWPR
HKIQSKHRML DEKSLQEKLK YFPVCVNTKI HQEDDAEEGL GSLPRNISSL SSLLLFNTTE
NLYKKYVFLD PLAGAVTKTH VALETETEEK LFDAPLSITE RGQLDRQVAE NYFYVPDLGQ
VPEIDVPSYL PDLPGIAADL MYSADLGPGI APSAPSSAIP ELPTFSTESV EPSQADLQDP
GLLPPPPPPP PPPPPVMPTT VPPPPPLPQP TAPSEPARTA SEDSSKTVPA ASVQGAPKEV
VNPSTGRASL LESIRQAGGI GKANLRSVKE RKLEKKKQKE QEQVRATGQG GDLMSDLFNK
LVLRRKGISG KGPGASANPD APGSPAGAFA RMSDSIPPLP PPQQPPGEED EDDWES


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