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Zg1

 Q90410_DANRE            Unreviewed;       418 AA.
Q90410;
01-NOV-1996, integrated into UniProtKB/TrEMBL.
01-NOV-1996, sequence version 1.
28-MAR-2018, entry version 108.
SubName: Full=Zg1 {ECO:0000313|EMBL:AAA86090.1};
Name=gata1a {ECO:0000313|ZFIN:ZDB-GENE-980526-268};
Synonyms=gata1 {ECO:0000313|ZFIN:ZDB-GENE-980526-268},
zg1 {ECO:0000313|EMBL:AAA86090.1};
Danio rerio (Zebrafish) (Brachydanio rerio).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
Cyprinidae; Danio.
NCBI_TaxID=7955 {ECO:0000313|EMBL:AAA86090.1};
[1] {ECO:0000313|EMBL:AAA86090.1}
NUCLEOTIDE SEQUENCE.
TISSUE=Total embryo {ECO:0000313|EMBL:AAA86090.1};
PubMed=7479870; DOI=10.1073/pnas.92.23.10713;
Detrich H.W.III., Kieran M.W., Chan F.Y., Barone L.M., Yee K.,
Rundstadler J.A., Pratt S., Ransom D., Zon L.I.;
"Intraembryonic hematopoietic cell migration during vertebrate
development.";
Proc. Natl. Acad. Sci. U.S.A. 92:10713-10717(1995).
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EMBL; U18311; AAA86090.1; -; mRNA.
RefSeq; NP_571309.1; NM_131234.1.
UniGene; Dr.355; -.
ProteinModelPortal; Q90410; -.
SMR; Q90410; -.
GeneID; 30481; -.
KEGG; dre:30481; -.
CTD; 30481; -.
ZFIN; ZDB-GENE-980526-268; gata1a.
eggNOG; KOG1601; Eukaryota.
eggNOG; COG5641; LUCA.
HOVERGEN; HBG051705; -.
KO; K09182; -.
PhylomeDB; Q90410; -.
GO; GO:0005634; C:nucleus; IC:ZFIN.
GO; GO:0003700; F:DNA binding transcription factor activity; IDA:ZFIN.
GO; GO:0003690; F:double-stranded DNA binding; IDA:ZFIN.
GO; GO:0043565; F:sequence-specific DNA binding; IDA:ZFIN.
GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
GO; GO:0043009; P:chordate embryonic development; IMP:ZFIN.
GO; GO:0035162; P:embryonic hemopoiesis; IMP:ZFIN.
GO; GO:0048821; P:erythrocyte development; IMP:ZFIN.
GO; GO:0030218; P:erythrocyte differentiation; IMP:ZFIN.
GO; GO:0030225; P:macrophage differentiation; IMP:ZFIN.
GO; GO:0030224; P:monocyte differentiation; IMP:ZFIN.
GO; GO:0030099; P:myeloid cell differentiation; IGI:ZFIN.
GO; GO:0043066; P:negative regulation of apoptotic process; IMP:ZFIN.
GO; GO:0010629; P:negative regulation of gene expression; IMP:ZFIN.
GO; GO:0030223; P:neutrophil differentiation; IMP:ZFIN.
GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IMP:ZFIN.
GO; GO:0060215; P:primitive hemopoiesis; IMP:ZFIN.
GO; GO:0045637; P:regulation of myeloid cell differentiation; IMP:ZFIN.
Gene3D; 3.30.50.10; -; 2.
InterPro; IPR016374; TF_GATA-2/3.
InterPro; IPR000679; Znf_GATA.
InterPro; IPR013088; Znf_NHR/GATA.
Pfam; PF00320; GATA; 2.
PIRSF; PIRSF003027; TF_GATA-1/2/3; 2.
PRINTS; PR00619; GATAZNFINGER.
SMART; SM00401; ZnF_GATA; 2.
PROSITE; PS00344; GATA_ZN_FINGER_1; 2.
PROSITE; PS50114; GATA_ZN_FINGER_2; 2.
2: Evidence at transcript level;
Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00094,
ECO:0000256|SAAS:SAAS01008217};
Zinc {ECO:0000256|PROSITE-ProRule:PRU00094,
ECO:0000256|SAAS:SAAS01008217};
Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00094,
ECO:0000256|SAAS:SAAS01008217}.
DOMAIN 232 287 GATA-type. {ECO:0000259|PROSITE:PS50114}.
DOMAIN 286 339 GATA-type. {ECO:0000259|PROSITE:PS50114}.
SEQUENCE 418 AA; 45663 MW; CDB1773A8FD5801B CRC64;
MENSSEPSRW VSPGLLSPDP LVNYTTDSGL LPPVDVDEPF YSSSETDLLP SYYSTSVQSR
ASSSYRHSPV RQVYSSQSIL GNIQWLDNSA GHSLNSPYNP TSTVWSSSPF PKTPLHSHTS
TSIYQNTATP SFTSPKEGFP SPSRDGKDSP RLQEVLKAER LSPMSGSGSS FLNLSSATGG
VYGPSPHMLS PYGSYMSTSQ DYSSAALYST GGPWMSPSSY SPKLRNKMRL SPPEARECVN
CGATATPLWR QDGTGHYLCN ACGLYHKMNG QNRPLIRPKK RLIVSKRAGT QCANCHTSTT
TLWRRNASGE PVCNACGLYF KLHNVNRPLT MKKDGIQTRN RKVSNRNKKG KKNAASEVYP
DMSHMAPPDE HVGAYSLNPG PLLSYSHPAH LLPTSTLHSS TTLPYTHHPN SGMMPTLV


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