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Index / Abfron / â_Amyloid 42, Human / Product Detail : LF-P0051 â_Amyloid 42, Human
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Jun
25th
#LF-P0051 â_Amyloid 42, Human
| Price : | 287 | EUR |
| 326 | USD | |
| 223 | GBP | |
| 1208 | Zloty | |
| 38504 | JPY | |
| 2219 | NOK | |
| 2377 | SEK | |
| 325 | CHF |
Product name : â_Amyloid 42, Human
Catalog number : LF-P0051
Quantity: 0.5 mg
Availability: Yes
Supplier name : Abfron
Data sheet: Ask more or other datasheet now !
About this Product :
â_Amyloid 42, Human Human samples 80 % of the research is conducted on human samples. GENTAUR suppliers human normal cells, cell lines, RNA extracts and lots of antibodies and ELISA kits to Human proteins as well as â_Amyloid 42, Human .http://mybiofast.com/ver.php?search=human+&submit=Search
More Details about
Amyloid beta (Aβ or A beta) is a protein fragment of 39–43 amino acids that is the main constituent of amyloid plaques in the brains of Alzheimer's disease patients. Aβ is formed after sequential cleavage of the amyloid precursor protein (APP, transmembrane glycoprotein) by the β- and γ-secretases. . The major species generated are Aβ40 and Aβ42. The latter is more hydrophobic and more apt to aggregate and thus is considered to be primarily pathogenic, consistent with the phenotype of the major familial ADcausing mutations. Increases in either total Aβ levels or the relative concentration of the 42-amino acid form have been implicated in the pathogenesis of both familial and sporadic Alzheimer's disease. The 42-mers are the most amyloidogenic form of the peptide.
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Bibliography :
[28456479] Age-specific and sex-specific prevalence of cerebral β-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50-95 years: a cross-sectional study.
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