Gentaur Molecular :Arbor \ DyLight \ A001F-50UG

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Tel (408) 780-0908, Fax (408) 780-0908, sales@genprice.com

Index / Arbor / DyLight / Product Detail : A001F-50UG DyLight
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Aug
23th

#A001F-50UG DyLight

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Price :	323	EUR
	366	USD
	250	GBP
	1357	Zloty
	43228	JPY
	2491	NOK
	2669	SEK
	365	CHF

Product name : DyLight

Catalog number : A001F-50UG

Quantity: 50

Availability: Yes

Supplier name : Arbor

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More Details about

FEATURES

VERSATILE - Western blotting, Immunoassay and Immunoprecipitation
PURE - Supplied labeled in PBS with no carrier protein
BRIGHT - Strong fluorescence - 3 mole DyLight 488/IgG

DESCRIPTION

The Arbor Assays AbX^™ DyLight^{^®} 488-labeled Glutathione (GSH) Mouse Monoclonal Antibody is produced from the Protein A purified antibody by treatment with DyLight^{^®} 488 NHS ester. It will fluorescently label GSH-protein complexes under non-reducing conditions. Similar fluorescent properties to FITC.

Glutathione (GSH) is the highest concentration non-protein thiol in mammalian cells and is present in concentrations of 0.5 to 10 mM. GSH plays a key role in many biological processes, including the synthesis of proteins and DNA, the transport of amino acids, and the protection of cells against oxidation. Harmful hydrogen peroxide cellular levels are minimized by the enzyme glutathione peroxidase (GP) using GSH as a reductant. The oxidized GSH dimer, GSSG, is formed from GSH and peroxide by the GP reaction. An important role of
GSSG in the NFkB activating signal cascade is suggested by the fact that the potent NFkB inducer TPA increases intracellular GSSG levels and GSSG/GSH ratios.