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Product name : 6_Chloropurine
Catalog number : CB0124
Supplier name : BioBasic
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52062 Aachen Deutschland
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Handelsregister Aachen HR B 16058
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[TRAF6 RNF85] TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85)
[LRP6] Low-density lipoprotein receptor-related protein 6 (LRP-6)
[Lrp6] Low-density lipoprotein receptor-related protein 6 (LRP-6)
[IL6 IFNB2] Interleukin-6 (IL-6) (B-cell stimulatory factor 2) (BSF-2) (CTL differentiation factor) (CDF) (Hybridoma growth factor) (Interferon beta-2) (IFN-beta-2)
[Pax6 Pax-6 Sey] Paired box protein Pax-6 (Oculorhombin)
[GAS6 AXLLG] Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand)
[ABCC6 ARA MRP6] Multidrug resistance-associated protein 6 (ATP-binding cassette sub-family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter E) (MOAT-E)
[HDAC6 KIAA0901 JM21] Histone deacetylase 6 (HD6) (EC 22.214.171.124)
[Gata6] Transcription factor GATA-6 (GATA-binding factor 6)
[TRAF1 EBI6] TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
[FAS APT1 FAS1 TNFRSF6] Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)
[SMAD6 MADH6] Mothers against decapentaplegic homolog 6 (MAD homolog 6) (Mothers against DPP homolog 6) (SMAD family member 6) (SMAD 6) (Smad6) (hSMAD6)
[Cdk5 Cdkn5 Crk6] Cyclin-dependent-like kinase 5 (EC 126.96.36.199) (CR6 protein kinase) (CRK6) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
[MSH6 GTBP] DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160)
[DAXX BING2 DAP6] Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein)
[PAX6 AN2] Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin)
[Il6 Il-6] Interleukin-6 (IL-6) (B-cell hybridoma growth factor) (Interleukin HP-1)
[CDK6 CDKN6] Cyclin-dependent kinase 6 (EC 188.8.131.52) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)
[Traf6] TNF receptor-associated factor 6 (EC 6.3.2.-) (E3 ubiquitin-protein ligase TRAF6)
[MAP2K6 MEK6 MKK6 PRKMK6 SKK3] Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 184.108.40.206) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)
[BCL6 BCL5 LAZ3 ZBTB27 ZNF51] B-cell lymphoma 6 protein (BCL-6) (B-cell lymphoma 5 protein) (BCL-5) (Protein LAZ-3) (Zinc finger and BTB domain-containing protein 27) (Zinc finger protein 51)
[TRIP6 OIP1] Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1)
[TP53 P53] Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
[Il6 Il-6] Interleukin-6 (IL-6)
[ITGA6] Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)]
[NEK6] Serine/threonine-protein kinase Nek6 (EC 220.127.116.11) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512)
[PPARGC1A LEM6 PGC1 PGC1A PPARGC1] Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1-alpha) (PPAR-gamma coactivator 1-alpha) (PPARGC-1-alpha) (Ligand effect modulator 6)
[PRMT6 HRMT1L6] Protein arginine N-methyltransferase 6 (EC 18.104.22.1689) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6) (Histone-arginine N-methyltransferase PRMT6)
[CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1] Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6) (p21)
[FASLG APT1LG1 CD95L FASL TNFSF6] Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]
 9-Norbornyl-6-chloropurine (NCP) induces cell death through GSH depletion-associated ER stress and mitochondrial dysfunction.
 New carbocyclic N(6)-substituted adenine and pyrimidine nucleoside analogues with a bicyclo[2.2.1]heptane fragment as sugar moiety; synthesis, antiviral, anticancer activity and X-ray crystallography.
 [The search of novel inhibitors of HIV-1 integrase among 5-(4-halogenophenyl)-5-oxopentyl derivatives of nucleic bases].
 Synthesis of novel thiopurine pyranonucleosides: evaluation of their bioactivity.
 New antitumor 6-chloropurine nucleosides inducing apoptosis and G2/M cell cycle arrest.
 Transport mechanisms of a novel antileukemic and antiviral compound 9-norbornyl-6-chloropurine.
 Synthesis of novel purine-based coxsackievirus inhibitors bearing polycylic substituents at the N-9 position.
 Microwave-assisted synthesis of novel purine nucleosides as selective cholinesterase inhibitors.
 New carbocyclic nucleoside analogues with a bicyclo[2.2.1]heptane fragment as sugar moiety; synthesis, X-ray crystallography and anticancer activity.
 9-Norbornyl-6-chloropurine is a novel antileukemic compound interacting with cellular GSH.
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