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Index / Ray Biotech / Mouse Anti-Human LMO2 / Product Detail : 129-10414 Mouse Anti-Human LMO2
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#129-10414 Mouse Anti-Human LMO2

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  Price : 690   EUR
783   USD
535   GBP
2898   Zloty
92325   JPY
5321   NOK
5701   SEK
780   CHF

Product name : Mouse Anti-Human LMO2

Catalog number : 129-10414

Quantity: 100

Availability: Yes

Supplier name : Ray Biotech

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About this Product :

Mouse Anti-Human LMO2 antibody storage GENTAUR recommends for long therm storage to freeze at -24 C. For short time storage up to 30 days we suggest fridge storage at 1 to 10 C. Prevent multiple freeze taw cycles of Mouse Anti-Human LMO2.

Mouse Anti-Human LMO2 storing antibdies for longer storage periods of the Mouse Anti-Human LMO2 we recommend - 21C or lower and for short periods lees than 1 month we suggest +5C fridge temperatures.

Mouse Anti-Human LMO2 Human samples 80 % of the research is conducted on human samples. GENTAUR suppliers human normal cells, cell lines, RNA extracts and lots of antibodies and ELISA kits to Human proteins as well as Mouse Anti-Human LMO2.

More Details about


Target Name


Target Species


Application Notes

This product detects a band of approximately 24kDa in Raji cell lysates.

Recommended Applications
Immunofluorescence, Immunohistology - Paraffin, Western Blotting


This product recognizes the human LIM-only protein (LMO2), a 24kD transcription factor that interacts with DNA binding proteins such as TAL1/SCL and GATA1. In early development, LMO2 is expressed in the central nervous system and a wide range of tissue, and in adults in myeloid and erythroid precursors, in normal germinal center B-cells, endothelial cells and parts of the brain. LMO2 plays a vital role in early stages of hematopoiesis and in regulating yolk-sac erythropoiesis in mice. Studies suggest that it may also play a role in angiogenesis.

A major cause of T-cell acute lymphoblastic leukemia (T-ALL) is the aberrant activation of the TAL1/SCL, LMO1/2, and NOTCH1 oncogenes. Activation of the Notch signalling pathway by mutations in either the gamma-secretase or PEST domains are found in more than 50% of all T-ALL, including LMO2-induced T-ALL, and studies using mouse models, have show that activation of Notch co-operates with Scl/Lmo1 in inducing T-ALL. .

Aberrant expression of LMO2 has also been linked to certain types of B-cell lymphoma, and LMO2 is reported to be expressed in prostate cancer, with overexpression possibly linked to cancer progression.


Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.


Supplied as:
Purified IgG - liquid
Phosphate buffered saline
Format Type:


IgG concentration 1.0 mg/ml


Purified GST-LMO2 fusion protein
0.09% Sodium Azide (NaN3)
This product
Cells from immunised mice were fused with cells of the K6H6B5 myeloma cell line.


Purified IgG prepared by affinity chromatography on Protein G



This product is furnished for LABORATORY RESEARCH USE ONLY. Not for diagnostic or therapeutic use.


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