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Index / Ray Biotech / Rabbit Anti-SIGIRR, C-terminus / Product Detail : 129-10609 Rabbit Anti-SIGIRR, C-terminus
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Sep
25th

#129-10609 Rabbit Anti-SIGIRR, C-terminus

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  Price : 643   EUR
729   USD
498   GBP
2700   Zloty
86027   JPY
4958   NOK
5312   SEK
727   CHF

Product name : Rabbit Anti-SIGIRR, C-terminus

Catalog number : 129-10609

Quantity: 100

Availability: Yes

Supplier name : Ray Biotech

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About this Product :

Rabbit Anti-SIGIRR, C-terminus antibody storage GENTAUR recommends for long therm storage to freeze at -24 C. For short time storage up to 30 days we suggest fridge storage at 1 to 10 C. Prevent multiple freeze taw cycles of Rabbit Anti-SIGIRR, C-terminus.
http://mybiofast.com/ver.php?search=anti-&submit=Search

Rabbit Anti-SIGIRR, C-terminus storing antibdies for longer storage periods of the Rabbit Anti-SIGIRR, C-terminus we recommend - 21C or lower and for short periods lees than 1 month we suggest +5C fridge temperatures.
http://mybiofast.com/ver.php?search=antibodie&submit=Search

More Details about

 

Target Name

SIGIRR

Target Species

Mouse

Species Detected

Human

Application Notes

This product detects a band of approximately 43kDa in A549 cell lysate

Recommended Applications
Immunohistology - Frozen, Western Blotting

Specificity

This product recognizes the Single Ig IL-1-related receptor (SIGIRR), a member of the Toll-like receptor-interleukin 1 receptor superfamily, defined by an intracellular Toll-IL-1R (TIR) domain. SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signalling pathways. It interacts with TLR4, TLR5, TLR9 and IL-1R through the extracellular Ig domain, or the intracellular TIR domain. The Ig domain interferes with the heterodimerisation of IL-1R while the intracellular TIR domain inhibits both IL-1 and LPS signalling by attenuating the recruitment of receptor-proximal signalling components to TLR4. SIGIRR is expressed in kidney, colon, small intestine, lung, spleen and liver. It is not expressed in brain and muscle.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Concentration

IgG concentration 1.0mg/ml

Preparation

Antiserum to SIGIRR (CT) was raised by repeated immunisation of with highly purified antigen. Purified IgG was prepared from whole serum by immunoaffinity chromatography.

Immunogen:
A peptide corresponding to 15 amino acids at the carboxy terminus of mouse SIGIRR.
Preservative:
0.02% Sodium Azide (NaN3)

Purification

Purified IgG prepared by Immunoaffinity chromatography

 
 
 
 
 

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY. Not for diagnostic or therapeutic use.

 

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