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Monoclonal Antibody, ELISA Kit, Polyclonal Antibody, Recombinant/Purified Protein.
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Index / Biovis / Tranylcypromine Hemisulfate; Appearance White solid / Product Detail : 1816-25 Tranylcypromine Hemisulfate; Appearance White solid
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May
25th
#1816-25 Tranylcypromine Hemisulfate; Appearance White solid
| Price : | 126 | EUR |
| 143 | USD | |
| 97 | GBP | |
| 530 | Zloty | |
| 16890 | JPY | |
| 973 | NOK | |
| 1043 | SEK | |
| 142 | CHF |
Product name : Tranylcypromine Hemisulfate; Appearance White solid
Catalog number : 1816-25
Quantity: 25 mg
Availability: Yes
Supplier name : Biovis
Data sheet: Ask more or other datasheet now !
More Details about
Alternate Name/Synonyms: Trans (±)-2-Phenylcyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA; Parnate; Jatrosom
Peptide sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 13492-01-8
Molecular Formula: C₉H₁₁N.1/2H₂SO₄
Molecular Weight: 182.2
Purity: ≥99% by TLC
Solubility: H₂O (25 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Description: An inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC50 <2 µM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021 (Cat. No. 1677-5, 25), causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4.
Handling: Protect from air and moisture
USAGE: For Research Use Only! Not For Use in Humans.
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Related Genes :
[CYP3A4 CYP3A3] Cytochrome P450 3A4 (EC 1.14.13.-) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.13.157) (Albendazole monooxygenase) (EC 1.14.13.32) (Albendazole sulfoxidase) (CYPIIIA3) (CYPIIIA4) (Cholesterol 25-hydroxylase) (EC 1.14.14.1) (Cytochrome P450 3A3) (Cytochrome P450 HLp) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Nifedipine oxidase) (Quinine 3-monooxygenase) (EC 1.14.13.67) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97)
[CYP1A2] Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3)
[CYP2D6 CYP2DL1] Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6) (Cholesterol 25-hydroxylase) (Cytochrome P450-DB1) (Debrisoquine 4-hydroxylase)
[CYP2C9 CYP2C10] Cytochrome P450 2C9 (EC 1.14.13.-) ((R)-limonene 6-monooxygenase) (EC 1.14.13.80) ((S)-limonene 6-monooxygenase) (EC 1.14.13.48) ((S)-limonene 7-monooxygenase) (EC 1.14.13.49) (CYPIIC9) (Cholesterol 25-hydroxylase) (EC 1.14.99.38) (Cytochrome P-450MP) (Cytochrome P450 MP-4) (Cytochrome P450 MP-8) (Cytochrome P450 PB-1) (S-mephenytoin 4-hydroxylase)
[CYP2C19] Cytochrome P450 2C19 (EC 1.14.13.-) ((R)-limonene 6-monooxygenase) (EC 1.14.13.80) ((S)-limonene 6-monooxygenase) (EC 1.14.13.48) ((S)-limonene 7-monooxygenase) (EC 1.14.13.49) (CYPIIC17) (CYPIIC19) (Cytochrome P450-11A) (Cytochrome P450-254C) (Mephenytoin 4-hydroxylase)
[CYP2A6 CYP2A3] Cytochrome P450 2A6 (EC 1.14.13.-) (1,4-cineole 2-exo-monooxygenase) (CYPIIA6) (Coumarin 7-hydroxylase) (Cytochrome P450 IIA3) (Cytochrome P450(I))
[MAOB] Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)
[MAOA] Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A)
[CYP2E1 CYP2E] Cytochrome P450 2E1 (EC 1.14.13.-) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (CYPIIE1) (Cytochrome P450-J) [Cleaved into: Cytochrome P450 2E1, N-terminally processed]
[Kdm1b Aof1 Lsd2] Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2)
Bibliography :
[28390942] Fluorinated tranylcypromine analogues as inhibitors of lysine-specific demethylase 1 (LSD1, KDM1A).
[28237611] Abnormal pregnancy outcome associated with high-dose maternal tranylcypromine therapy: Case report and literature review.
[27989747] Chronic postnatal monoamine oxidase inhibition affects affiliative behavior in rat pupso.
[27989416] Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity.
[27922229] Reversible Cerebral Vasoconstriction Syndrome and Monoamine Oxidase Inhibitors.
[27893888] Potential Neuroprotective Effects of an LSD1 Inhibitor in Retinal Ganglion Cells via p38 MAPK Activity.
[27885768] Gram-Scale Synthesis of Chiral Cyclopropane-Containing Drugs and Drug Precursors with Engineered Myoglobin Catalysts Featuring Complementary Stereoselectivity.
[27715253] An Overview of Analytical Methods for the Determination of Monoamine Oxidase Inhibitors in Pharmaceutical Formulations and Biological Fluids.
[27664690] CYP2D6 and CYP2A6 biotransform dietary tyrosol into hydroxytyrosol.
[27481483] Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch.
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