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Index / Trevigen / anti-phos histone H2AX / Product Detail : 4418-APC-020 anti-phos histone H2AX
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Dec
9th

#4418-APC-020 anti-phos histone H2AX

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  Price : 138   EUR
156   USD
107   GBP
579   Zloty
18465   JPY
1064   NOK
1140   SEK
156   CHF

Product name : anti-phos histone H2AX

Catalog number : 4418-APC-020

Quantity: 20 ul

Availability: Yes

Supplier name : Trevigen

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More Details about

Background: Histone H2AX is a 14 kDa ubiquitous member of the H2A histone family that contains an evolutionarily conserved SQ motif at the C-terminus in eukaryotes. Serine 139 within this motif becomes rapidly phosphorylated to yield a form known as g-H2AX in response to double-strand DNA damage and apoptosis. Phosphorylation reaches half its maximum between 1-3 minutes after DNA damage occurs, and hundreds to several thousand molecules of g-H2AX are present per double-strand break. This antibody is unique in only detecting double-strand DNA breaks.
Physical State: Peptide affinity purified rabbit polyclonal antibody raised against synthetic phosphorylated peptide (CKATQA[pS]QEY). Provided at 0.5 μg/μl in phosphate buffered saline buffer with 50% glycerol.
Specificity: Recognizes human and mouse g-H2AX.
Storage: -20°C.
Applications: Suitable for Western blotting and immunocytochemistry (IC). For Western blot analysis, a starting dilution of 1:1,000 – 1:2,500 is recommended, whereas for IC, a starting dilution of 1:100 is recommended. Empirical determination of antibody concentration is required for optimal results.

 

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