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Index / Neuromi / Calbindin, monoclonal antibody, mouse, 100 ul... / Product Detail : MO20016-100 Calbindin, monoclonal antibody, mouse, 100 ul...
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  Price : 258   EUR
293   USD
200   GBP
1087   Zloty
34639   JPY
1996   NOK
2139   SEK
292   CHF

Product name : Calbindin, monoclonal antibody, mouse, 100 ul...

Catalog number : MO20016-100


Availability: Yes

Supplier name : Neuromi

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About this Product :

Calbindin, monoclonal antibody, mouse, 100 ul... antibody storage GENTAUR recommends for long therm storage to freeze at -24 C. For short time storage up to 30 days we suggest fridge storage at 1 to 10 C. Prevent multiple freeze taw cycles of Calbindin, monoclonal antibody, mouse, 100 ul....

Calbindin, monoclonal antibody, mouse, 100 ul... mus musculus murine Calbindin, monoclonal antibody, mouse, 100 ul... detects proteins from variouse species most likely human.

Calbindin, monoclonal antibody, mouse, 100 ul...
Calbindin, monoclonal antibody, mouse, 100 ul... is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against. If used correctly and according the protocol, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications. Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches; in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required.

More Details about


Catalog Number Size    
MO20016 100 ug    
Type: Mouse IgG
Applications: IHC
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ; ; ;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All
Format: Supernatant - liquid
Immunogen: Prokaryotic recombinant protein corresponding to the majority of the calbindin molecule.

Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It functions as a buffer of cytosolic calcium and is found in the brain, kidney, gut and pancreatic islets. In normal brain, calbindin (28kD) has been identified in medium sized neurons of the neuropil of the matrix compartment of the striatum, the woolly fiber arrangements of the globus pallidus and the fiber structures of the pars reticula of the substantia nigra.

Image: Calbindin staining of Human brain, cerebellum. Note cytoplasmic staining of Purkinje cells and neuronal processes. Paraffin section.

The normal expression of calbindin is modified in patients with progressive supranuclear palsy, striatal degeneration and Huntington's disease (HD). In HD, alterations to the dendritic arbors and spiny striatal neurons may be visualized by immunohistochemistry for calbindin. In moderate grades of HD, proliferative changes have been found in these areas and in severe grades, degenerative changes have been noted. A proportion of dendritic cells within the light zone of germinal centers are also noted to be positive for calbindin.

Calbindin, via the ventrolateral periaqueductal gray (vlPAG), is thought  to play a role in the reactions characteristic of deep pain.


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