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Index / Neuromi / Nitric Oxide Synthase, monoclonal antibody, mouse, 100 ul. / Product Detail : MO20029-100 Nitric Oxide Synthase, monoclonal antibody, mouse, 100 ul.
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  Price : 234   EUR
265   USD
181   GBP
984   Zloty
31347   JPY
1806   NOK
1935   SEK
264   CHF

Product name : Nitric Oxide Synthase, monoclonal antibody, mouse, 100 ul.

Catalog number : MO20029-100


Availability: Yes

Supplier name : Neuromi

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About this Product :

Nitric Oxide Synthase, monoclonal antibody, mouse, 100 ul. antibody storage GENTAUR recommends for long therm storage to freeze at -24 C. For short time storage up to 30 days we suggest fridge storage at 1 to 10 C. Prevent multiple freeze taw cycles of Nitric Oxide Synthase, monoclonal antibody, mouse, 100 ul..

Nitric Oxide Synthase, monoclonal antibody, mouse, 100 ul. mus musculus murine Nitric Oxide Synthase, monoclonal antibody, mouse, 100 ul. detects proteins from variouse species most likely human.

Nitric Oxide Synthase, monoclonal antibody, mouse, 100 ul.
Nitric Oxide Synthase, monoclonal antibody, mouse, 100 ul. is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against. If used correctly and according the protocol, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications. Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches; in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required.

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Type: Mouse IgG
Applications: IHC
ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; WB=Western blotting; FC=Flow Cytometry; IP=Immunoprecipitation; E=ELISA; NB=Neutralization of Bioactivity; FACS; FM=Fluorescent Micsroscopy; ; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; TPE=Targeted Protein Expression; ; ; AC=Adherent Cell Assays; ; ; NAC=Non-adherent Cell Assays; ; ; BSC-CM5= Biacore Sensor Chip CM5; ; ;
Species Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins
Format: Affinity Purified - liquid
Immunogen: Recombinant protein corresponding to a portion of the C-terminus of the mature human nitric oxide synthase-1 protein.


Human nitric oxide synthases are a family of enzymes responsible for the synthesis of nitric oxide from L-arginine and molecular oxygen. There are at least three nitric oxide synthases; NOS I, also known as neuronal NOS or nNOS, NOS II, which is referred to as inducible NOS or iNOS and NOS III, also known as endothelial NOS or eNOS. As suggested by their nomenclature, these enzymes have different cellular distribution and are subjected to different regulatory mechanisms. NOS III, like NOS I, is a constitutive form of NOS and produces picomolar quantities of nitric oxide (NO) which plays a role in signal transmission and results in physiological effects. In the gastrointestinal tract, NO plays a protective role where it has direct microbiocidal properties and acts as a first line of mucosal defence against luminal organisms in the stomach.

nNOS plays a role in  the upregulation of microglial phospho-p38 MAPK. Such p38 MAPK activation in microglia is consistent with a potential role in the development of morphine antinociceptive tolerance.

Image: Nitric oxide synthase-1 staining of human small intestine.Note cytoplasmic staining of enteric ganglia. Paraffin section.


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