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Index / SBI / MicroRNA Tools miRZip-21 anti-miR-21 microRNA construct / Product Detail : MZIP21-PA-1 MicroRNA Tools miRZip-21 anti-miR-21 microRNA construct
#MZIP21-PA-1 MicroRNA Tools miRZip-21 anti-miR-21 microRNA construct
Product name : MicroRNA Tools miRZip-21 anti-miR-21 microRNA construct
Catalog number : MZIP21-PA-1
Quantity: Bacterial Streak
Supplier name : SBI
Data sheet: Ask more or other datasheet now !
About this Product :MicroRNA Tools miRZip-21 anti-miR-21 microRNA construct antibody storage GENTAUR recommends for long therm storage to freeze at -24 C. For short time storage up to 30 days we suggest fridge storage at 1 to 10 C. Prevent multiple freeze taw cycles of MicroRNA Tools miRZip-21 anti-miR-21 microRNA construct.
MicroRNA Tools miRZip-21 anti-miR-21 microRNA construct storing antibdies for longer storage periods of the MicroRNA Tools miRZip-21 anti-miR-21 microRNA construct we recommend - 21C or lower and for short periods lees than 1 month we suggest +5C fridge temperatures.
MicroRNA Tools miRZip-21 anti-miR-21 microRNA construct rna research rna is not so stable and very sticky. Rnases are abundand on hans and everywhere. SoreRNA at -75C and use rnase free.
More Details about
Suppression of cell invasion and tumor metastasis by miRZip-21 and increased metastasis using miRZip-145
To investigate the roles of miR-21 (oncogenic microRNA) and miR-145 (tumor suppressor microRNA) in breast cancer, cell invasion assays of MDA-MB-231 breast cancer cells were performed after lentiviral transduction with control vector lentivirus (Control) or miRZip-21 or miRZip-145 lentivirus. Matrigel chamber assays were then used to screen for invasive phenotypes.
After 20 h, invasion cells attached to the lower surface were fixed, followed by staining with 0.05% crystal violet. The number of invaded cells on the membrane was then counted under a microscope. Representative fields of invasive cells on the membrane are shown at the bottom for the Control and miRZip-21 or miRZip-145 treated cells.
The miRZip-21 lentivirus expressing anti-mir-21 small RNAs inhibited metastasis by 80% and the miRZip-145 lentivirus expressing anti-miR-145 RNAs increased metastasis by 60%. Additionally, the miRZip-145 lentivirus inhibited endogenous miR-145 and elevated protein expression levels of the miR-145 target oncogene c-Myc.
• List of miRZip clones
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WP1963: The effect of Glucocorticoids on target gene expression
Related Genes :
[AGO2 EIF2C2] Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
[FMR1] Synaptic functional regulator FMR1 (Fragile X mental retardation protein 1) (FMRP) (Protein FMR-1)
[DICER1 DICER HERNA KIAA0928] Endoribonuclease Dicer (EC 22.214.171.124) (Helicase with RNase motif) (Helicase MOI)
[Fmr1 Fmr-1] Synaptic functional regulator FMR1 (Fragile X mental retardation protein 1 homolog) (FMRP) (Protein FMR-1) (mFmr1p)
[MIR17HG C13orf25 MIRH1 MIRHG1] Putative microRNA 17 host gene protein (Putative microRNA host gene 1 protein)
[Sirt1 Sir2l1] NAD-dependent protein deacetylase sirtuin-1 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (SIR2alpha) (Sir2) (mSIR2a) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]
[ZC3H12A MCPIP MCPIP1] Bifunctional endoribonuclease and deubiquitinase ZC3H12A [Includes: Endoribonuclease ZC3H12A (EC 3.1.-.-); Deubiquitinase ZC3H12A (EC 126.96.36.199) (Monocyte chemotactic protein-induced protein 1) (MCP-induced protein 1) (MCPIP-1) (Regnase-1) (Reg1) (Zinc finger CCCH domain-containing protein 12A)]
[DROSHA RN3 RNASE3L RNASEN] Ribonuclease 3 (EC 188.8.131.52) (Protein Drosha) (Ribonuclease III) (RNase III) (p241)
[Lin28a Lin28 Tex17] Protein lin-28 homolog A (Lin-28A) (Testis-expressed protein 17)
[TARBP2 TRBP] RISC-loading complex subunit TARBP2 (TAR RNA-binding protein 2) (Trans-activation-responsive RNA-binding protein)
[Ezh2 Enx1h] Histone-lysine N-methyltransferase EZH2 (EC 184.108.40.206) (ENX-1) (Enhancer of zeste homolog 2)
[LIN28A CSDD1 LIN28 ZCCHC1] Protein lin-28 homolog A (Lin-28A) (Zinc finger CCHC domain-containing protein 1)
[Ago2 Eif2c2 Kiaa4215] Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer)
[Dicer1 Dicer Mdcr] Endoribonuclease Dicer (EC 220.127.116.11) (Double-strand-specific ribonuclease mDCR-1)
[DRB1 HYL1 At1g09700 F21M12.9] Double-stranded RNA-binding protein 1 (Protein HYPONASTIC LEAVES 1) (dsRNA-binding protein 1) (AtDRB1)
[DGCR8 C22orf12 DGCRK6 LP4941] Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8)
[TNRC6A CAGH26 KIAA1460 TNRC6] Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
[Fmr1 FXR CG6203] Synaptic functional regulator FMR1 (Fragile X mental retardation syndrome-related protein 1) (dFMR1)
[PNPT1 PNPASE] Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 18.104.22.168) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)
[AGO1 EIF2C1] Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99)
[IGF2BP1 CRDBP VICKZ1 ZBP1] Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
[UBC24 PHO2 At2g33770 T1B8.8] Probable ubiquitin-conjugating enzyme E2 24 (EC 22.214.171.124) (AtPHO2) (E2 ubiquitin-conjugating enzyme 24) (Ubiquitin carrier protein 24) (Ubiquitin-protein ligase 24)
[mael CG11254] Protein maelstrom
[APOBEC3G MDS019] DNA dC->dU-editing enzyme APOBEC-3G (EC 3.5.4.-) (APOBEC-related cytidine deaminase) (APOBEC-related protein) (ARCD) (APOBEC-related protein 9) (ARP-9) (CEM-15) (CEM15) (Deoxycytidine deaminase) (A3G)
[Fmr1] Synaptic functional regulator FMR1 (Fragile X mental retardation protein 1 homolog) (FMRP) (Protein FMR-1)
[RAN ARA24 OK/SW-cl.81] GTP-binding nuclear protein Ran (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
[ADAR ADAR1 DSRAD G1P1 IFI4] Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 126.96.36.199) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)
[Zcchc11 Kiaa0191 Tut4] Terminal uridylyltransferase 4 (TUTase 4) (EC 188.8.131.52) (Zinc finger CCHC domain-containing protein 11)
[PLK2 SNK] Serine/threonine-protein kinase PLK2 (EC 184.108.40.206) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)
[RNF213 ALO17 C17orf27 KIAA1554 KIAA1618 MYSTR] E3 ubiquitin-protein ligase RNF213 (EC 3.6.4.-) (EC 6.3.2.-) (ALK lymphoma oligomerization partner on chromosome 17) (Mysterin) (RING finger protein 213)
 The accuracy of microRNA-210 in diagnosing lung cancer: a systematic review and meta-analysis.
 Identification of rifampin-regulated functional modules and related microRNAs in human hepatocytes based on the protein interaction network.
 An integrative genomics approach for identifying novel functional consequences of PBRM1 truncated mutations in clear cell renal cell carcinoma (ccRCC).
 Plasma miR-142 accounting for the missing heritability of CYP3A4/5 functionality is associated with pharmacokinetics of clopidogrel.
 Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells.
 Knockdown of NEAT1 restrained the malignant progression of glioma stem cells by activating microRNA let-7e.
 Antigen specific immune response in Chlamydia muridarum genital infection is dependent on murine microRNAs-155 and -182.
 Epigenetic Activation of Wnt/β-Catenin Signaling in NAFLD-Associated Hepatocarcinogenesis.
 Mucosal MicroRNAs Expression Profiles before and after Exclusive Enteral Nutrition Therapy in Adult Patients with Crohn's Disease.
 MicroRNA-144 regulates cancer cell proliferation and cell-cycle transition in acute lymphoblastic leukemia through the interaction of FMN2.
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