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Index / Abfron / anti-Nitrotyrosine, Rabbit polyclonal to Nitrotyrosine, Isotype IgG, Host Rabbit / Product Detail : LF-PA0067 anti-Nitrotyrosine, Rabbit polyclonal to Nitrotyrosine, Isotype IgG, Host Rabbit
#LF-PA0067 anti-Nitrotyrosine, Rabbit polyclonal to Nitrotyrosine, Isotype IgG, Host Rabbit
Product name : anti-Nitrotyrosine, Rabbit polyclonal to Nitrotyrosine, Isotype IgG, Host Rabbit
Catalog number : LF-PA0067
Quantity: 100 ul
Supplier name : Abfron
Data sheet: Ask more or other datasheet now !
About this Product :anti-Nitrotyrosine, Rabbit polyclonal to Nitrotyrosine, Isotype IgG, Host Rabbit rabbit polyclonal These antibodies are very stable and can be stored up to 2 months at fridge temperature under 10C. Do not freeze taw, rather use anti-Nitrotyrosine, Rabbit polyclonal to Nitrotyrosine, Isotype IgG, Host Rabbit from the fridge if your use is less than 1 or 2 weeks.
More Details about
Nitrotyrosine has been identified as an indicator of cell damage and inflammation, as well as the production of NO. Nitrotyrosine is a relatively stable product formed from various reaction pathways. One of them is the reaction of peroxynitrite with tyrosine. Peroxynitrite formed from superoxide and nitric oxide radicals mediates tyrosine nitration reactions on proteins resulting in inactivation of certain house-keeping enzymes as well as endogenous antioxidant enzymes such as catalase and superoxide dismutase. Nitrotyrosine has been implicated in the pathogenesis of many inflammatory, infectious and degenerative human diseases such as Alzheimer’s disease, atherosclerosis, asthma and a variety of conditions mediated by endothelial injury. Oxidative stress has been indicated as a mechanism of secondary neuronal injury in traumatic brain injury. Nitrotyrosine in the cerebrospinal fluid may be an in vivo marker of oxidative nitric oxide damage. Several pathologies of the cardiovascular system are also associated with an augmented production of nitric oxide and/or superoxide-derived oxidants that lead to nitroxidative stress. The high contents of iron (heme) in certain tissues such as heart and vascular smooth muscle cells could serve as a biological base for iron toxicity on free radical-mediated tissue damage, including formation of nitrotyrosine.
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WP1963: The effect of Glucocorticoids on target gene expression
Related Genes :
[TP53 P53] Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
[MAPK14 CSBP CSBP1 CSBP2 CSPB1 MXI2 SAPK2A] Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 184.108.40.206) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)
[BCL2] Apoptosis regulator Bcl-2
[rseA mclA yfiJ b2572 JW2556] Anti-sigma-E factor RseA (Regulator of SigE) (Sigma-E anti-sigma factor RseA) (Sigma-E factor negative regulatory protein)
[OPRM1 MOR1] Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)
[Bcl2 Bcl-2] Apoptosis regulator Bcl-2
[KMT2A ALL1 CXXC7 HRX HTRX MLL MLL1 TRX1] Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 220.127.116.11) (ALL-1) (CXXC-type zinc finger protein 7) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]
[rsrA SCO5217] Anti-sigma factor RsrA (Regulator of SigR) (Sigma-R anti-sigma factor RsrA)
[APEX1 APE APE1 APEX APX HAP1 REF1] DNA-(apurinic or apyrimidinic site) lyase (EC 3.1.-.-) (EC 18.104.22.168) (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (APE-1) (REF-1) (Redox factor-1) [Cleaved into: DNA-(apurinic or apyrimidinic site) lyase, mitochondrial]
[AR DHTR NR3C4] Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
[ASF1 CIA1 YJL115W J0755] Histone chaperone ASF1 (Anti-silencing function protein 1) (yASF1)
[BRCA1 RNF53] Breast cancer type 1 susceptibility protein (EC 6.3.2.-) (RING finger protein 53)
[MSH2] DNA mismatch repair protein Msh2 (hMSH2) (MutS protein homolog 2)
[MLH1 COCA2] DNA mismatch repair protein Mlh1 (MutL protein homolog 1)
[F9] Coagulation factor IX (EC 22.214.171.124) (Christmas factor) (Plasma thromboplastin component) (PTC) [Cleaved into: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain]
[PML MYL PP8675 RNF71 TRIM19] Protein PML (Promyelocytic leukemia protein) (RING finger protein 71) (Tripartite motif-containing protein 19)
[OR1F1 OLFMF OR1F10 OR1F4 OR1F5 OR1F6 OR1F7 OR1F8 OR1F9] Olfactory receptor 1F1 (Olfactory receptor 16-35) (OR16-35) (Olfactory receptor 1F10) (Olfactory receptor 1F4) (Olfactory receptor 1F5) (Olfactory receptor 1F6) (Olfactory receptor 1F7) (Olfactory receptor 1F8) (Olfactory receptor 1F9) (Olfactory receptor OR16-4)
[PTEN MMAC1 TEP1] Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 126.96.36.199) (EC 188.8.131.52) (EC 184.108.40.206) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
[F8 F8C] Coagulation factor VIII (Antihemophilic factor) (AHF) (Procoagulant component) [Cleaved into: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain]
[INSR] Insulin receptor (IR) (EC 220.127.116.11) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
[LTF GIG12 LF] Lactotransferrin (Lactoferrin) (EC 3.4.21.-) (Growth-inhibiting protein 12) (Talalactoferrin) [Cleaved into: Lactoferricin-H (Lfcin-H); Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C]
[OTUD7B ZA20D1] OTU domain-containing protein 7B (EC 18.104.22.168) (Cellular zinc finger anti-NF-kappa-B protein) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne)
[OR1E1 OR1E5 OR1E6 OR1E9P] Olfactory receptor 1E1 (Olfactory receptor 13-66) (OR13-66) (Olfactory receptor 17-2/17-32) (OR17-2) (OR17-32) (Olfactory receptor 1E5) (Olfactory receptor 1E6) (Olfactory receptor 5-85) (OR5-85) (Olfactory receptor OR17-18) (Olfactory receptor-like protein HGMP07I)
[rslA Rv0736] Anti-sigma-L factor RslA (Regulator of SigL) (Sigma-L anti-sigma factor RslA)
[rsbW usfX Rv3287c] Anti-sigma-F factor RsbW (Anti-sigma-F factor UsfX) (Regulator of SigF) (Sigma-F anti-sigma factor RsbW)
[Tp53 P53 Trp53] Cellular tumor antigen p53 (Tumor suppressor p53)
[SCN5A] Sodium channel protein type 5 subunit alpha (HH1) (Sodium channel protein cardiac muscle subunit alpha) (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5)
[AKT1 PKB RAC] RAC-alpha serine/threonine-protein kinase (EC 22.214.171.124) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
[ASF1A CGI-98 HSPC146] Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A) (hAsf1) (hAsf1a) (CCG1-interacting factor A) (CIA) (hCIA)
[PARK7] Protein deglycase DJ-1 (DJ-1) (EC 3.1.2.-) (EC 3.5.1.-) (Oncogene DJ1) (Parkinson disease protein 7)
 Methotrexate administration induces differential and selective protein tyrosine nitration and cysteine nitrosylation in the subcellular organelles of the small intestinal mucosa of rats.
 Cisplatin-induced apoptosis in auditory, renal, and neuronal cells is associated with nitration and downregulation of LMO4.
 Systemic Induction of NO-, Redox-, and cGMP Signaling in the Pumpkin Extrafascicular Phloem upon Local Leaf Wounding.
 ANSID: A Solid-Phase Proteomic Approach for Identification and Relative Quantification of Aromatic Nitration Sites.
 Nitroproteins in Human Astrocytomas Discovered by Gel Electrophoresis and Tandem Mass Spectrometry.
 Down regulation of NO signaling in Trypanosoma cruzi upon parasite-extracellular matrix interaction: changes in protein modification by nitrosylation and nitration.
 Oxidative stress impairs function and increases redox protein modifications in human spermatozoa.
 Effect of flaxseed on choroid-sclera complex thickness and on LDL oxidation in the sclera, choroid and retina of diet-induced hypercholesterolaemic rabbits.
 Mycobacteria counteract a TLR-mediated nitrosative defense mechanism in a zebrafish infection model.
 Thioredoxin reductase was nitrated in the aging heart after myocardial ischemia/reperfusion.
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