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Index / FabGennix / Human Lactoferrin, Host species: Rabbit, Polyclonal antibody / Product Detail : Hlac-101AP Human Lactoferrin, Host species: Rabbit, Polyclonal antibody
#Hlac-101AP Human Lactoferrin, Host species: Rabbit, Polyclonal antibody
Product name : Human Lactoferrin, Host species: Rabbit, Polyclonal antibody
Catalog number : Hlac-101AP
Supplier name : FabGennix
Data sheet: Ask more or other datasheet now !
About this Product :Human Lactoferrin, Host species: Rabbit, Polyclonal antibody antibody storage GENTAUR recommends for long therm storage to freeze at -24 C. For short time storage up to 30 days we suggest fridge storage at 1 to 10 C. Prevent multiple freeze taw cycles of Human Lactoferrin, Host species: Rabbit, Polyclonal antibody .
Human Lactoferrin, Host species: Rabbit, Polyclonal antibody rabbit polyclonal These antibodies are very stable and can be stored up to 2 months at fridge temperature under 10C. Do not freeze taw, rather use Human Lactoferrin, Host species: Rabbit, Polyclonal antibody from the fridge if your use is less than 1 or 2 weeks.
More Details about
Lactoferrin, an iron-binding glycoprotein with an approximate molecular weight of 80 kDa. The protein has two iron binding domains each housing one Fe(3+) and the synergistic CO(3)(2-) ion (1). The crystal structure of differic form of human lactoferrin at 2.2A resolution exhibit 5330 protein atoms, 2Fe+2 , 2CO3-2 and 98 carbohydrate atoms (1).
Lactoferrin is absorbed from intestine by apical; side of the membrane and localized to the nuclei (2). Anti-lactoferrin antibodies were detected in some patients with rheumatoid arthritis and systemic lupus erythematousus and other muscle diseases (3). Intravenous infusion of lactoferrin is also protective against lethal dose of E coli induce bacterimia by a mechanism that down regulate neutrophil TNF alfa secretion (4). Recombinant human lactoferrin (rhLF), expressed and extracted from rice seed, is being evaluated for use as a dietary supplement to treat iron deficiency and/or iron deficiency-induced anemia. Lactoferrin has been shown to have a role in immune system and in early development of embryo. A specific receptor for lactoferrin binding has been implicated in human fetal intestine (5). Early embryonic localization of lactiferrin by IHC has suggested its presence in various tissues including intestinal epitheliuem, kiney, and various regions of the brain.
FabGennix International Inc. has produced affinity purified antibdies to human and bovine lactoferrin proteins. These antibodies are generated in rabbit using purified human or bovine lactoferrin proteins. The lactoferrin antibodies were then affinity purufied using immobilized antigenic proteins and pre-adsorbed on an immobilized heterologus lactoferin matrix to remove the cross-reacting antibodies. Limited quantities of blocking protein is also available (please inquire). FabGennix, Inc., will also provide Western blot positive controls for most of these antibodies in ready-to-use buffer for easy identification of respective proteins.
For research use only, not for diagnostic or therapeutic use.
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WP2107: pathways in human cancer
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[TP53 P53] Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
[ELANE ELA2] Neutrophil elastase (EC 22.214.171.124) (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)
[RACK1 GNB2L1 HLC7 PIG21] Receptor of activated protein C kinase 1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Small ribosomal subunit protein RACK1) [Cleaved into: Receptor of activated protein C kinase 1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed)]
[AR DHTR NR3C4] Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
[EGFR ERBB ERBB1 HER1] Epidermal growth factor receptor (EC 126.96.36.199) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
[SCN5A] Sodium channel protein type 5 subunit alpha (HH1) (Sodium channel protein cardiac muscle subunit alpha) (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5)
[FBN1 FBN] Fibrillin-1 [Cleaved into: Asprosin]
[CTNNB1 CTNNB OK/SW-cl.35 PRO2286] Catenin beta-1 (Beta-catenin)
[CCNDBP1 DIP1 GCIP HHM] Cyclin-D1-binding protein 1 (Grap2 and cyclin-D-interacting protein) (Human homolog of Maid)
[F8 F8C] Coagulation factor VIII (Antihemophilic factor) (AHF) (Procoagulant component) [Cleaved into: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain]
[SIRT1 SIR2L1] NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]
[BRCA1 RNF53] Breast cancer type 1 susceptibility protein (EC 188.8.131.52) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
[AKAP13 BRX HT31 LBC] A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47)
[UBE3A E6AP EPVE6AP HPVE6A] Ubiquitin-protein ligase E3A (EC 184.108.40.206) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)
[HBB] Hemoglobin subunit beta (Beta-globin) (Hemoglobin beta chain) [Cleaved into: LVV-hemorphin-7; Spinorphin]
[APP A4 AD1] Amyloid beta A4 protein (ABPP) (APPI) (APP) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Beta-amyloid precursor protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]
[gag-pol] Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 220.127.116.11) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 18.104.22.168) (EC 22.214.171.124) (EC 126.96.36.199) (Exoribonuclease H) (EC 188.8.131.52) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]
[ZAK MLTK HCCS4] Mitogen-activated protein kinase kinase kinase MLT (EC 184.108.40.206) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)
[GOLGA2] Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95)
[LRRK2 PARK8] Leucine-rich repeat serine/threonine-protein kinase 2 (EC 220.127.116.11) (Dardarin)
[TGFB1 TGFB] Transforming growth factor beta-1 (TGF-beta-1) [Cleaved into: Latency-associated peptide (LAP)]
[AKT1 PKB RAC] RAC-alpha serine/threonine-protein kinase (EC 18.104.22.168) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
[EPHA3 ETK ETK1 HEK TYRO4] Ephrin type-A receptor 3 (EC 22.214.171.124) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)
[DNAJA1 DNAJ2 HDJ2 HSJ2 HSPF4] DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
[TRIP13 PCH2] Pachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13)
[SRC SRC1] Proto-oncogene tyrosine-protein kinase Src (EC 126.96.36.199) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
[SCN1A NAC1 SCN1] Sodium channel protein type 1 subunit alpha (Sodium channel protein brain I subunit alpha) (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1)
[APOE] Apolipoprotein E (Apo-E)
[KCNQ1 KCNA8 KCNA9 KVLQT1] Potassium voltage-gated channel subfamily KQT member 1 (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1) (Voltage-gated potassium channel subunit Kv7.1)
[FGFR2 BEK KGFR KSAM] Fibroblast growth factor receptor 2 (FGFR-2) (EC 188.8.131.52) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
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