GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc 6017 Snell Ave, Ste 357, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908,

Index / FabGennix / PDE2A, Host species: Rabbit, Polyclonal antibody / Product Detail : PD2A-101AP PDE2A, Host species: Rabbit, Polyclonal antibody
Related keywords:


#PD2A-101AP PDE2A, Host species: Rabbit, Polyclonal antibody

Ask technical file .

  Price : 410   EUR
466   USD
318   GBP
1725   Zloty
54965   JPY
3168   NOK
3394   SEK
464   CHF

Product name : PDE2A, Host species: Rabbit, Polyclonal antibody

Catalog number : PD2A-101AP

Quantity: 200ul

Availability: Yes

Supplier name : FabGennix

ask pdf gentaur products Data sheet: Ask more or other datasheet now !

About this Product :

PDE2A, Host species: Rabbit, Polyclonal antibody antibody storage GENTAUR recommends for long therm storage to freeze at -24 C. For short time storage up to 30 days we suggest fridge storage at 1 to 10 C. Prevent multiple freeze taw cycles of PDE2A, Host species: Rabbit, Polyclonal antibody .

PDE2A, Host species: Rabbit, Polyclonal antibody rabbit polyclonal These antibodies are very stable and can be stored up to 2 months at fridge temperature under 10C. Do not freeze taw, rather use PDE2A, Host species: Rabbit, Polyclonal antibody from the fridge if your use is less than 1 or 2 weeks.

More Details about

Cyclic nucleotides are important intracellular second messengers which play important role variety of signal transduction process.  The cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases.  One of the many phosphodiesterases that compartmentalized and hydrolyze cAMP and cGMP in to AMP and GMP respectively are phosphodiesterase type 2  There are two member of PDE2A gene are cloned and designated as PD2A and PDE2B (Rascon et. al., 2002).  Each of the PDE2A and PDE2B genes are 2793 Bases and 930 amino acids with an apparent MW of 100 kDA.  The catalytic domain of PDE2A is homologous to all other 11 PDE family members.  The PDE2A has specificity for cAMP with Km of 2.4 uM and its activity is modulated by the presence of cGMP.  In contrast, the PDE2B does not hydrolyze cGMP nor its activity is altered by the presence of cGMP.   Western blot analyses of PDE2A reveals a variety of tissues including neocortex, cerebellum, heart, kidney lungs, pulmonary artery and skeletal muscle (Sadhu et. al., 2002).  The PDE2A expression was evident in venous arterial endothelial cells but not in arterial endothelial cells (Sadhu et. al., 1999).  The PDE2A expression was also noted in corpus cavernosum along with a wide repertoire of other PDEs enzymes (Kuthe et. al., 1999).   
FabGennix Inc. also provides antibodies to other PDE family members.  The PDE-selective antibodies are PDE-selective, family subtype-selective and family-subtype-variant selective antibodies for detailed analyses of cyclic nucleotide signaling pathways.  We have generated two PDE2A-selective antibodies (PD2A-101AP, FITC-PDE2A and Biotin-PDE2A) that were generated from epitopes close to C-terminal regions.  The polyclonal antibody (PD2A-101AP) labels a 103 kDa PDE2A protein in rat brain and other tissues.  The PDE2A-specific antiserum has no cross reactivity against PDE2B or with other PDE family members tested so far. 
The PDE2A-selective antibodies (PD2A-101AP ) was generated using cyclic peptide methodology that results in higher titer and specificity.  PDE2A-selective antibody is also available in affinity purified form for confocal, Western blotting and immunocytochemical analyses.  The affinity purified antibodies are also conjugated to FITC and Biotin for direct applications in IHC FACS assay.  FabGennix Inc. will also conjugate antibodies with enzymes, fluorescent probes upon request at extra charge.

For research use only, not for diagnostic or therapeutic use

Contact us about this product :

Our team will respond you as soon as possible !

Email :
Skype :
Name :
Phone :
address :
Question, Comment ... :
arrow security gentaurPlease retype this code below:
FabGennix \ PDE2A,_Host_species:_Rabbit,_Polyclonal_antibody_ \ PD2A_101AP
Reload Image


GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45 | Gentaur

Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411 | Gentaur



9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017


Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925 | Gentaur

Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123

GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897 | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U

tel:0911876558 | Gentaur

ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: | Gentaur
IBAN: BG11FINV91501014771636

GENTAUR Poland Sp. z o.o.

ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48       | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556


Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94 | Gentaur