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Index / Trevigen / Cultrex In Vitro Angiogenesis Assay Endothelial Cell Invasion Kit / Product Detail : 3471-096-K Cultrex In Vitro Angiogenesis Assay Endothelial Cell Invasion Kit
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Apr
23th
#3471-096-K Cultrex In Vitro Angiogenesis Assay Endothelial Cell Invasion Kit
Price : | 421 | EUR |
478 | USD | |
327 | GBP | |
1770 | Zloty | |
56397 | JPY | |
3250 | NOK | |
3482 | SEK | |
476 | CHF |
Product name : Cultrex In Vitro Angiogenesis Assay Endothelial Cell Invasion Kit
Catalog number : 3471-096-K
Quantity: 96 tests
Availability: Yes
Supplier name : Trevigen
Data sheet: Ask more or other datasheet now !
More Details about
During angiogenesis, which is the formation of neovasculature associated with wound healing and a host of disease states including tumor growth, endothelial cells invade through the basement membrane to form sprouting vessels, which in turn invade hypoxic tissue. Trevigen's Cultrex® In Vitro Angiogenesis Assay Endothelial Cell Invasion Kit was created in an effort to accelerate the screening process for compounds that influence vascular endothelial cell digestion through a basement membrane extract (BME) layer. This kit offers a flexible, standardized, 96 well high-throughput format for quantitating endothelial invasion, in vitro, in response to chemoattractants and/or inhibiting compounds. This assay employs a simplified Boyden chamber-like design with an 8 micron polyethylene terephthalate (PET) membrane. Sulforaphane [1-isothiocyanato-(4R)-methylsulfinyl)-butane], a naturally occurring cancer chemopreventive agent, is provided as a control for inhibition of in vitro endothelial cell invasion through Cultrex® BME. Detection of cell invasion is quantified using Calcein-AM. Calcein AM is internalized by the cells, and intracellular esterases cleave the acetomethylester (AM) moiety. Free Calcein fluoresces brightly, and this fluorescence may be used to quantitate the number of cells that have invaded or migrated using a standard curve.
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Related products : Cultrex In Vitro Angiogenesis Assay Endothelial Cell Invasion Kit
Gentaurpub
Pathways :
WP1004: Kit Receptor Signaling Pathway
WP1011: T Cell Receptor Signaling Pathway
WP1025: B Cell Receptor Signaling Pathway
WP1043: Calcium Regulation in the Cardiac Cell
WP1069: Integrin-mediated cell adhesion
WP1078: G1 to S cell cycle control
WP1083: Cell cycle
WP1121: Kit Receptor Signaling Pathway
WP1130: T Cell Receptor Signaling Pathway
WP1144: B Cell Receptor Signaling Pathway
WP1159: Calcium Regulation in the Cardiac Cell
WP1185: Integrin-mediated cell adhesion
WP1195: G1 to S cell cycle control
WP1200: Cell cycle
WP1341: Kit Receptor Signaling Pathway
WP1345: T Cell Receptor Signaling Pathway
WP1354: B Cell Receptor Signaling Pathway
WP1365: Calcium Regulation in the Cardiac Cell
WP1386: Integrin-mediated cell adhesion
WP1393: Cell cycle
WP1411: Cell Division: First embryonic mitosis
WP147: Kit Receptor Signaling Pathway
WP1539: Angiogenesis
WP1753: Angiogenesis
WP1775: Cell Cycle Checkpoints
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