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#5000-001-01 Rat Mesenchymal Cells
Product name : Rat Mesenchymal Cells
Catalog number : 5000-001-01
Quantity: 1 vial
Supplier name : Trevigen
Data sheet: Ask more or other datasheet now !
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Cultrex Rat Mesenchymal Cells
Catalog #: 5000-001-01
Rat Mesenchymal Stem Cells
Mesenchymal Stem Cells (MSC), also known as marrow stromal cells, are a self-renewing population of multipotent cells present in bone marrow and many other adult tissues. MSC can be isolated from bone marrow by adherence to plastic, and can differentiate into multiple lineage- specific cells that form bone, fat, cartilage, muscle, neuronal cells and tendon. Due to their multilineage potential, they can be useful tools for a wide range of therapeutic and basic research, including transplantation studies and studies examining the repair of cardiac tissue, bone, cartilage, and tendons often using 3-D matrices. The generation of dependable information that can be shared between laboratories requires a consistent, highly purified source of MSC that have maintained their multipotency, as demonstrated by their ability to differentiate to different tissue types. Isolation of MSC is both a time and resource consuming process which can now be eliminated. A readily available and qualified source of cells will substantially decrease MSC preparation time required prior to experimentation.
Trevigen's RMSC are provided as a frozen ampoule containing 1 x 106 passage 3 cells that are greater than 99% pure. These cells can be maintained in an undifferentiated state when grown in Trevigen's qualified RMSC Medium supplemented with RMSC qualified FBS or induced to differentiate into adipogenic or osteogenic phenotype when growth media are supplemented with reagents contained in Trevigen's differentiation kits. Trevigen's RMSC can undergo 10 doublings without alteration in cell morphology or differentiation potential.
- Primary Mesenchymal Stem Cells isolated and purified from Rat Bone Marrow.
- Qualified medium and fetal bovine serum to support undifferentiated growth of rat mesenchymal stem cells.
Therapeutic and basic research, including transplantation studies and studies examining the repair of cardiac tissue, bone, cartilage, and tendons often using 3-D matrices.
Cultrex® Rat Mesenchymal Stem Cell Liquid Nitrogen
1. Phinney DG, Prockop DJ. 2007. Concise Review: Mesenchymal Stem/Multipotent Stromal Cells: The State of Transdifferentiation and Models of Tissue Repair-Current Views. Stem Cells 25:2896-2902.
2. Kolf CM, Cho E, Tuan RS. 2007. Biology of Adult Mesenchymal Stem Cells: Regulation of Niche, Self-Renewal and Differentiation. Arthritis Research and Therapy 9:204.
3. Javazon EH, Colter DC, Schwarz EJ, Prockop DJ. 2001. Rat Marrow Stromal Cells are More Sensative to Plating Density and Expand More Rapidly from Single-Cell-Derived Colonies than Human Marrow Stromal Cells. Stem Cells 19:219-225.
4. Li Yi, McIntosh K, Chen J, Zhang C, Gao, Q, Borneman J, Ragniski K, Mitchell J, Shen L, Zhang J, Lu D, Chopp M. 2006. Allogeneic bone marrow stromal cells promote glial-axonal remodeling without immunologic sensitization after stroke in rats. Experimental Neurology 198:313-25.
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Related Genes :
[Cacna1c Cach2 Cacn2 Cacnl1a1 Cchl1a1] Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Rat brain class C) (RBC) (Voltage-gated calcium channel subunit alpha Cav1.2)
[Cacna1d Cach3 Cacn4 Cacnl1a2 Cchl1a2] Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Rat brain class D) (RBD) (Voltage-gated calcium channel subunit alpha Cav1.3)
[Kcnb1] Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (Voltage-gated potassium channel subunit Kv2.1)
[App] Amyloid beta A4 protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) (Amyloid precursor protein) (Amyloidogenic glycoprotein) (AG) (Beta-amyloid precursor protein) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Gamma-CTF(50)); C31]
[Drd2] D(2) dopamine receptor (Dopamine D2 receptor)
[Tgfb1] Transforming growth factor beta-1 (TGF-beta-1) [Cleaved into: Latency-associated peptide (LAP)]
[Src] Proto-oncogene tyrosine-protein kinase Src (EC 188.8.131.52) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
[Gja1 Cxn-43] Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
[Cacna1a Cach4 Cacn3 Cacnl1a4] Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide, isoform 4) (Rat brain class A) (RBA-I) (Voltage-gated calcium channel subunit alpha Cav2.1)
 Major urinary protein (MUP) (Allergen Rat n I) (Alpha(2)-euglobulin) (Alpha-2u-globulin) (alpha-2u globulin PGCL1) (allergen Rat n 1) [Cleaved into: 15.5 kDa fatty acid-binding protein (15.5 kDa FABP)]
[Ptk2b Fak2 Pyk2] Protein-tyrosine kinase 2-beta (EC 184.108.40.206) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2)
[Oprm1 Ror-b] Mu-type opioid receptor (M-OR-1) (MOR-1) (Opioid receptor B)
[Akt1] RAC-alpha serine/threonine-protein kinase (EC 220.127.116.11) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (RAC-PK-alpha)
[Nr3c1 Grl] Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
[Nos1 Bnos] Nitric oxide synthase, brain (EC 18.104.22.168) (BNOS) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Peptidyl-cysteine S-nitrosylase NOS1)
[Hspa8 Hsc70 Hsc73] Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)
[Notch1] Neurogenic locus notch homolog protein 1 (Notch 1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
[Hmgb1 Hmg-1 Hmg1] High mobility group protein B1 (Amphoterin) (Heparin-binding protein p30) (High mobility group protein 1) (HMG-1)
[Esr2 Erbeta Nr3a2] Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
[Lyn] Tyrosine-protein kinase Lyn (EC 22.214.171.124) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
[Myc] Myc proto-oncogene protein (Proto-oncogene c-Myc) (Transcription factor p64)
[Mtor Frap1 Raft1] Serine/threonine-protein kinase mTOR (EC 126.96.36.199) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1)
[Dlg4 Dlgh4 Psd95] Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
[Gper1 Cmkrl2 Gper Gpr30 Gpr41] G-protein coupled estrogen receptor 1 (Chemoattractant receptor-like 2) (G protein-coupled estrogen receptor 1) (G-protein coupled receptor 30) (G-protein coupled receptor 41) (Membrane estrogen receptor) (mER)
[Park2 Prkn] E3 ubiquitin-protein ligase parkin (EC 6.3.2.-)
[Sirt1] NAD-dependent protein deacetylase sirtuin-1 (EC 3.5.1.-)
[Ptgs2 Cox-2 Cox2] Prostaglandin G/H synthase 2 (EC 188.8.131.52) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)
[Kcna2] Potassium voltage-gated channel subfamily A member 2 (RAK) (RBK2) (RCK5) (Voltage-gated potassium channel subunit Kv1.2)
[Prkcz Pkcz] Protein kinase C zeta type (EC 184.108.40.206) (nPKC-zeta)
[Kcnd2] Potassium voltage-gated channel subfamily D member 2 (RK5) (Shal1) (Voltage-gated potassium channel subunit Kv4.2)
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