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Index / BPS Bioscience / FAP assay kit / Product Detail : 80210 FAP assay kit
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Dec
7th

#80210 FAP assay kit

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  Price : 1052   EUR
1194   USD
816   GBP
4422   Zloty
140849   JPY
8118   NOK
8698   SEK
1190   CHF

Product name : FAP assay kit

Catalog number : 80210

Quantity: 100 reactions

Availability: Yes

Supplier name : BPS Bioscience

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More Details about

DESCRIPTION: Fibroblast Activation Protein, or FAP, is a 170 kDa dimer with
dipeptidase activity. FAP expression is seen on activated stromal fibroblasts in >90% of
all human carcinomas, suggesting a role in the development, growth and metastasis of
carcinomas. It is also involved in the control of wound healing and tissue repair. The
Fluorogenic FAP Assay Kit is designed to measure FAP activity using purified
FAP for screening and profiling applications. It comes in a convenient 96-well format, with
purified FAP enzyme, DPP substrate, and DPP assay buffer for 100 enzyme reactions.
The key to the Fluorogenic FAP Assay Kit is the fluorogenic substrate. Using this kit,
only one simple step on a microtiter plate is required for FAP reactions. The DPP
fluorometric substrate is incubated with a sample containing FAP enzyme to produce a
fluorophore that can then be measured using a fluorescence reader.

COMPONENTS:
FAP Assay Kit PDF and Protocol

Note: The AMC standard is included so the researcher can quatitatively determine the
specific activity of the enzyme using the AMC standard as a measure of how much
AMC substrate was cleaved to release free AMC.

APPLICATIONS: Great for studying enzyme kinetics and screening small molecular
inhibitors for drug discovery and HTS applications.

REFERENCES:
1. Edosada,C.Y. et al., J. Biol. Chem. 281 (11): 7437-7444 (2006).
2. Edosada,C.Y. et al., FEBS Lett. 580 (6): 1581-1586 (2006).

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