GENTAUR Molecular Products.
Monoclonal Antibody, ELISA Kit, Polyclonal Antibody, Recombinant/Purified Protein.
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Index / Biovis / Cyclopamine / Product Detail : 1578-5 Cyclopamine
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Sep
21th
#1578-5 Cyclopamine
| Price : | 262 | EUR |
| 297 | USD | |
| 203 | GBP | |
| 1101 | Zloty | |
| 35069 | JPY | |
| 2021 | NOK | |
| 2165 | SEK | |
| 296 | CHF |
Product name : Cyclopamine
Catalog number : 1578-5
Quantity: 5 mg
Availability: Yes
Supplier name : Biovis
Data sheet: Ask more or other datasheet now !
More Details about
Alternate Name/Synonyms: 11-deoxojervine
Appearance: Off-white solid
Formulation: N/A
CAS Number: 4449-51-8
Molecular Formula: C₂₇H₄₁NO₂
Molecular Weight: 411.62
Purity: ≥99%
Solubility: DMSO (4 mg/ml) and EtOH (5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Description: Cyclopamine blocks activation of the Hedgehog response pathway associated with mutations that either activate the proto-oncogene Smoothened (Smo) or inactivate the tumour suppressor Patched (Ptch) both of which encode multipass transmembrane proteins. Furthermore, it has been demonstrated that the inhibitory effect of cyclopamine results from its direct binding to the Smo heptahelical protein bundle
Handling: Teratogen!
USAGE: For Research Use Only! Not For Use in Humans.
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GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45
Fax 0032 16 50 90 45
info@gentaur.com | Gentaur
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CA 95123
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Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123
GENTAUR Nederland BV
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Kuiper 1
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Related Genes :
[] Smoothened (Fragment)
Bibliography :
[28921619] Alcohol Reduces Arterial Remodeling by Inhibiting Sonic Hedgehog-Stimulated Sca1(+) Progenitor Stem Cell Expansion.
[28887094] Salvianolic Acids for Injection (SAFI) promotes functional recovery and neurogenesis via sonic hedgehog pathway after stroke in mice.
[28849917] Tumor Microenvironment Modulation by Cyclopamine Improved Photothermal Therapy of Biomimetic Gold Nanorods for Pancreatic Ductal Adenocarcinomas.
[28849750] Deciphering structural stability and binding mechanisms of potential antagonists with smoothened protein.
[28840059] Dopamine Burden Induced the Inactivation of Sonic Hedgehog Signaling to Cognitive Decline in Minimal Hepatic Encephalopathy.
[28833104] Low folate metabolic stress reprograms DNA methylation-activated sonic hedgehog signaling to mediate cancer stem cell-like signatures and invasive tumour stage-specific malignancy of human colorectal cancers.
[28779609] Sonic Hedgehog promotes in vitro oocyte maturation and term development of embryos in Taiwan native goats.
[28747625] The regulation of Hh/Gli1 signaling cascade involves Gsk3β- mediated mechanism in estrogen-derived endometrial hyperplasia.
[28667508] Laser irradiation promotes the proliferation of mouse pre-osteoblast cell line MC3T3-E1 through hedgehog signaling pathway.
[28647274] Sonic hedgehog pathway suppression and reactivation accelerates differentiation of rat adipose-derived mesenchymal stromal cells toward insulin-producing cells.
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