GENTAUR Molecular Products.
Monoclonal Antibody, ELISA Kit, Polyclonal Antibody, Recombinant/Purified Protein.
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Index / Biovis / Cyclopamine / Product Detail : 1578-5 Cyclopamine
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Sep
25th
#1578-5 Cyclopamine
| Price : | 262 | EUR |
| 297 | USD | |
| 203 | GBP | |
| 1101 | Zloty | |
| 35069 | JPY | |
| 2021 | NOK | |
| 2165 | SEK | |
| 296 | CHF |
Product name : Cyclopamine
Catalog number : 1578-5
Quantity: 5 mg
Availability: Yes
Supplier name : Biovis
Data sheet: Ask more or other datasheet now !
More Details about
Alternate Name/Synonyms: 11-deoxojervine
Appearance: Off-white solid
Formulation: N/A
CAS Number: 4449-51-8
Molecular Formula: C₂₇H₄₁NO₂
Molecular Weight: 411.62
Purity: ≥99%
Solubility: DMSO (4 mg/ml) and EtOH (5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Description: Cyclopamine blocks activation of the Hedgehog response pathway associated with mutations that either activate the proto-oncogene Smoothened (Smo) or inactivate the tumour suppressor Patched (Ptch) both of which encode multipass transmembrane proteins. Furthermore, it has been demonstrated that the inhibitory effect of cyclopamine results from its direct binding to the Smo heptahelical protein bundle
Handling: Teratogen!
USAGE: For Research Use Only! Not For Use in Humans.
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GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45
Fax 0032 16 50 90 45
info@gentaur.com | Gentaur
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Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123
GENTAUR Nederland BV
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Related Genes :
[] Smoothened (Fragment)
Bibliography :
[27660224] Effect of Smo SiRNA-mediated Hedgehog Signaling Pathway Inhibition on Palatal Fusion.
[27639396] Role of Sonic Hedgehog Signaling in Oligodendrocyte Differentiation.
[27634330] Inhibitory effect of bufalin combined with Hedgehog signaling pathway inhibitors on proliferation and invasion and metastasis of liver cancer cells.
[27576501] Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats.
[27520724] Combination therapy of paclitaxel and cyclopamine polymer-drug conjugates to treat advanced prostate cancer.
[27510750] Sonic hedgehog protein regulates fibroblast growth factor 8 expression in metanephric explant culture from BALB/c mice: Possible mechanisms associated with renal morphogenesis.
[27481074] Polydatin ameliorates renal ischemia/reperfusion injury by decreasing apoptosis and oxidative stress through activating sonic hedgehog signaling pathway.
[27479943] Cover Image, Volume 117, Number 10, October 2016.
[27479354] Serial femtosecond crystallography datasets from G protein-coupled receptors.
[27470568] Urtica dioica leaves modulates hippocampal smoothened-glioma associated oncogene-1 pathway and cognitive dysfunction in chronically stressed mice.
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