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Index / Biovis / SB_431542 / Product Detail : 1674-1 SB_431542
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Sep
25th

#1674-1 SB_431542

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  Price : 177   EUR
201   USD
137   GBP
746   Zloty
23761   JPY
1369   NOK
1467   SEK
200   CHF

Product name : SB_431542

Catalog number : 1674-1

Quantity: 1 mg

Availability: Yes

Supplier name : Biovis

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More Details about

 

Alternate Name/Synonyms: 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 301836-41-9

Molecular Formula: C₂₂H₁₈N₄O₃

Molecular Weight: 384.39

Purity: ≥98% by HPLC

Solubility: DMSO (20 mg/ml) or EtOH (2 mg/ml)

Storage Temp.: -20°C

Shipping Conditions: gel pack

Description: A potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC₅₀ = 94 nM). It inhibits ALK4 only at higher concentrations (IC₅₀ = 140 nM). Suppresses renewal in embryonic and induced pluripotent stem (iPS) cells and promotes their differentiation through its effect on Smad signaling pathway.

Handling: Protect from air and light

USAGE: For Research Use Only! Not For Use in Humans.

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