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Index / Biovis / MG_132 / Product Detail : 1703-5 MG_132
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Dec
11th

#1703-5 MG_132

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  Price : 180   EUR
205   USD
140   GBP
759   Zloty
24190   JPY
1394   NOK
1493   SEK
204   CHF

Product name : MG_132

Catalog number : 1703-5

Quantity: 5 mg

Availability: Yes

Supplier name : Biovis

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More Details about

MOLECULAR WEIGHT: 475.6
CAS NUMBER: 133407-82-6
PURITY: >98% by HPLC; identity determined by MS.
APPEARANCE: White to off-white powder
SOLUBILITY: Soluble in DMSO (10 mg/ml)
STORAGE CONDITIONS: -20°C.
DESCRIPTION: A cell-permeable, potent, and reversible proteasome inhibitor (Ki = 4 nM). Reduces degradation of ubiquitinconjugated proteins in mammalian cells and permeable strains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. Activates c-Jun N-terminal kinase (JNK1), which initiates apoptosis. Inhibits NF-B activation (IC50 = 3μM). Prevents γ -secretase cleavage.


FOR RESEARCH USE ONLY! Not to be used on humans.


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