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Index / Signosis 2011 / Apoptosis_Associated miRNA Plate Array / Product Detail : MA-1002 Apoptosis_Associated miRNA Plate Array
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#MA-1002 Apoptosis_Associated miRNA Plate Array

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  Price : 514   EUR
584   USD
399   GBP
2161   Zloty
68850   JPY
3968   NOK
4252   SEK
582   CHF

Product name : Apoptosis_Associated miRNA Plate Array

Catalog number : MA-1002

Quantity: 2

Availability: Yes

Supplier name : Signosis 2011

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About this Product :

Apoptosis_Associated miRNA Plate Array rna research rna is not so stable and very sticky. Rnases are abundand on hans and everywhere. SoreRNA at -75C and use rnase free.
http://gentaur-search.com/save_search/rna.htm

Apoptosis_Associated miRNA Plate Array exosomes mirnas are available in and out of exosomes. However exosomes are the perfect and easier way to obtain most pure exosomes except the argonauts
http://openwetware.org/wiki/Brown_BIOL1220:Notebook/SynBio_in_Theory_and_Practice/Genes/Argonauts(miRNA_pathway)

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Benefits:
  • Simple Do miRNA detection as doing ELISA. It does not need enzymatic conversion from miRNA into cDNA. The entire assay procedure is “incubation and wash”.
  • Higher sensitivity and better discrimination power - The detection is approximately 1000 times more sensitive than miRNA Northern blot. In addition, it has higher discrimination power than miRNA Northern blot in differetiating miRNA isoforms.
  • Quantitative comparison The difference of two or more samples in the expression of a specific miRNA can be quantitatively analyzed.
 

miRNA Direct Hybridization Plate Array I

miRNAs are known to involve in multiple biological functions and abnormal expression is associated to human diseases such as cancers. They represent a promising new class of cancer biomarkers. A number of multiplex methods such as microarray or microbeads assays are commonly used for profiling the expression of multiple miRNAs simultaneously. However these methods need the conversion of the miRNA into a cDNA probe during analysis. Signosis has developed a simple miRNA direct hybridization plate array method, in which total RNA does not need any pre-treatment before hybridization. It is as simple as direct hybridization and detection. More importantly, total 48 miRNAs can be quantitatively analyzed and compared simultaneously with the sample assay.

 

List of Applicable miRNAs

  1 2 3 4 5 6 7 8 9 10 11 12
A let7b miR-17-5p miR-29a miR-132 miR-182 miR-206 let7b miR-17-5p miR-29a miR-132 miR-182 miR-206
B miR-1 miR-18a miR-34a miR-133 miR-192 miR-210 miR-1 miR-18a miR-34a miR-133 miR-192 miR-210
C miR-7 miR-19a miR-92 miR-143 miR-194 miR-214 miR-7 miR-19a miR-92 miR-143 miR-194 miR-214
D miR-9 miR-19b miR-101a miR-145 miR-196a miR-222 miR-9 miR-19b miR-101a miR-145 miR-196a miR-222
E miR-10b miR-20a miR-106a miR-146a miR-199a miR-223 miR-10b miR-20a miR-106a miR-146a miR-199a miR-223
F miR-15a miR-21 miR-107 miR-148a miR-200 miR-342 miR-15a miR-21 miR-107 miR-148a miR-200 miR-342
G miR-15b miR-24 miR-122a miR-155 miR-204 miR-372 miR-15b miR-24 miR-122a miR-155 miR-204 miR-372
H miR-16-1 miR-26a miR-125a miR-181a miR-205 U6 miR-16-1 miR-26a miR-125a miR-181a miR-205 U6



Apoptosis-Associated miRNA Plate Array 

Apoptosis involves a series of biochemical events leading to a characteristic cell morphology and death, including changes to the cell membrane, cell shrinkage, nuclear fragmentation, chromatin condensation, and chromosomal DNA fragmentation. It plays important roles in removing unwanted cells during development and homeostasis. Excessive apoptosis causes hypotrophy, such as in ischemic damage, whereas an insufficient amount results in uncontrolled cell proliferation, such as cancer. MicroRNAs are newly discovered small non-coding RNA molecules that regulate up to 30% of mammalian gene expression. Numerous miRNAs have been revealed to have an influence on the regulation of apoptotic cell signaling such as overexpression of miR-145, miR-216, miR-182, and miR-96 miRNA to decrease caspase-3 activation. Signosis developed a miRNA array for targeting 47 miRNAs that have been shown in literature to be involved in apoptosis. Profiling the expression of these miRNAs will facilitate in uncovering the regulation of miRNA in apoptosis.

 

 List of Applicable miRNAs

  1 2 3 4 5 6 7 8 9 10 11 12
A Let-7a miR-16 miR-142 miR-155 miR-202 miR-337 Let-7a miR-16 miR-142 miR-155 miR-202 miR-337
B Let-7b miR-21 miR-144 miR-182 miR-204 miR-338 Let-7b miR-21 miR-144 miR-182 miR-204 miR-338
C Let-7c miR-24 miR-145 miR-184 miR-210 miR-345 Let-7c miR-24 miR-145 miR-184 miR-210 miR-345
D miR-1 miR-25 miR-148 miR-188 miR-214 miR-368 miR-1 miR-25 miR-148 miR-188 miR-214 miR-368
E miR-7 miR-26 miR-150 miR-193a miR-216 miR-369-5p miR-7 miR-26 miR-150 miR-193a miR-216 miR-369-5p
F miR-10a miR-96 miR-151 miR-193b miR-218 miR-369-3p miR-10a miR-96 miR-151 miR-193b miR-218 miR-369-3p
G miR-15a miR-101 miR-152 miR-196a miR-224 miR-371 miR-15a miR-101 miR-152 miR-196a miR-224 miR-371
H miR-15b miR-133b miR-153 miR-197 miR-296 U6 miR-15b miR-133b miR-153 miR-197 miR-296
 

 

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