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Index / Signosis 2011 / NFkB_Regulated cDNA Plate Array / Product Detail : AP-0101 NFkB_Regulated cDNA Plate Array
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#AP-0101 NFkB_Regulated cDNA Plate Array

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  Price : 464   EUR
527   USD
360   GBP
1950   Zloty
62122   JPY
3580   NOK
3836   SEK
525   CHF

Product name : NFkB_Regulated cDNA Plate Array

Catalog number : AP-0101

Quantity: 4

Availability: Yes

Supplier name : Signosis 2011

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Human NFkB-Regulated cDNA Plate Array

NFkB is a ubiquitous transcription factor that plays a key role in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. Incorrect regulation of NFkB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. When NFkB is activated, it is dissociated from its inhibitor IkB and moves from the cytoplasm to the nucleus, where it binds to target DNA elements and positively regulates the transcription of genes involved in immune and inflammatory responses, cell growth control, and apoptosis. 
 

Signosis developed a plate-based array for profiling 20+ NFkB-regulated genes. By using this assay, researchers are able to screen up to three samples on a single microtiter plate to compare gene expression in three separate constructs side by side.

List of Applicable Genes

  1 2 3 4 5 6 7 8 9 10 11 12
A BCL2 IL6  Myc  BCL2 IL6  Myc  BCL2 IL6  Myc  BCL2 IL6  Myc 
B Beta-actin  IL8  NOS2  Beta-actin  IL8  NOS2  Beta-actin  IL8  NOS2  Beta-actin  IL8  NOS2 
C CCND1 GAPDH  p53 CCND1 GAPDH  p53 CCND1 GAPDH  p53 CCND1 GAPDH  p53
D Cox-2  IFNg TNFA  Cox-2  IFNg TNFA  Cox-2  IFNg TNFA  Cox-2  IFNg TNFA 
E FAS-L  IRF1  TNFR  FAS-L  IRF1  TNFR  FAS-L  IRF1  TNFR  FAS-L  IRF1  TNFR 
F IFNB1  MDR1 VCAM1 IFNB1  MDR1 VCAM1 IFNB1  MDR1 VCAM1 IFNB1  MDR1 VCAM1
G IL1A  MMP1  VEGFC IL1A  MMP1  VEGFC IL1A  MMP1  VEGFC IL1A  MMP1  VEGFC
H IL2 Myb Blank IL2 Myb Blank IL2 Myb Blank IL2 Myb Blank
 

 

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