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Index / Signosis 2011 / NFkB Filter Assay / Product Detail : FA-0001 NFkB Filter Assay
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#FA-0001 NFkB Filter Assay

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  Price : 546   EUR
620   USD
424   GBP
2296   Zloty
73144   JPY
4215   NOK
4517   SEK
618   CHF

Product name : NFkB Filter Assay

Catalog number : FA-0001

Quantity: 96

Availability: Yes

Supplier name : Signosis 2011

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More Details about

NFkB Filter Plate Assay

Nuclear factor-kB (NFκB) is a transcription factor that controls the expression of genes involved in immune responses, apoptosis, and cell cycle. NFκB can be activated by a variety of stimuli, including cytokines, T and B cell mitogens, viral proteins, and stress inducers. The stimulation leads to phosphorylation of its inhibitor IκB, which releases NF-κB from IkB complex. After dissociation, NFκB translocates from the cytoplasm into the nucleus, where it binds to its target DNA elements and positively regulates the transcription of its target genes. Monitoring the activity of NFκB is crucial to the studies of the mechanism underlying NFκB activation and its associated pathway. Signosis' NFkB filter plate assay  allows monitoring of NFkB activity in a high throughput manner. This kit can detect NFkB activity in mammalian samples including human, rat, and mouse samples. Meanwhile, the assay can be set up for a few samples with less tedious than non-radioactive gel shift assay or much safe than 32P based gel shift assay.

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