Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery
Publication Date : //
Autoimmune diseases (AID) are pathological states wherein a disturbance of the regulation of physiological autoimmune processes results in the appearance of antibodies, T lymphocytes, specific in respect to components of self tissues, causing structural and/or functional disturbances in target organs. Studies conducted in respect of the pathogenesis of AID deal with its main components: 1) mechanisms of oligo-polyclonal B-cellular activation; 2) participation of autoantibodies, immune complexes, DTH effectors in the development of autoimmune inflammation; 3) participation of cytotoxic lymphocytes in the realization of inflammation; 4) participation of cytokines and growth factors in AID development; 5) the role of endothelial cells and adhesion molecules in the formation of inflammation during AID; 6) mechanisms of sclerogenesis; 7) the role of macrophages, neutrophils, platelets in the development of AID; 8) mechanisms for self-support of the autoimmune process; 9) the role of disturbances in apoptosis mechanisms. An important role in the realization of inflammation during autoimmune reactions belongs to various mediators of inflammation: prostaglandins, activated oxygen forms, proteinases and their inhibitors, vasoactive amines, nitrogen oxides, components of the complement system, and kinins. Early diagnosis of AID and improvements in the scheme of pharmacotherapy have made it possible to achieve substantial successes in treatment. The prospects of increasing the effectiveness of therapy is linked to the appearance of a new generation of preparations, developed on the base of profound knowledge of immunopathogenesis of organ specific and organ non-specific AID: the use of "anti-inflammatory cytokines", soluble cytokine receptors, antagonists of cytokine receptors, monoclonal antibodies to cytokines and membrane antigens of lymphocytes, inducers of apoptosis and others.
Authors : Shirinskiy Valery S. ,
Related products :
52062 Aachen Deutschland
Support Karolina Elandt
Fax: (+49) 241 56 00 47 88
Logistic :0241 40 08 90 86
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
firstname.lastname@example.org | Gentaur
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123
Canada Montreal +15149077481
Ceská republika Praha +420246019719
Finland Helsset +358942419041
Magyarország Budapest +3619980547
US New York+17185132983
No related Items
Related Genes :
 [Autoimmune Rheumatic Diseases - Problems of Immunopathology and Personalized Treatment].
 Signaling networks in MS: a systems-based approach to developing new pharmacological therapies.
 Current concepts and future directions for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies.
 [Ocular myasthenia gravis].
 [The otologic manifestation of Wegener's granulomatosis--review of contemporary achievements in diagnostics and treatment].
 Behavioural symptoms and impairments in multiple sclerosis: a systematic review and meta-analysis.
 Otologic symptoms as initial manifestation of wegener granulomatosis: diagnostic dilemma.
 Diagnosis and treatment difficulties in 18-year-old male patient with hereditary hemochromatosis, chronic hepatitis B, Gilbert syndrome and ulcerative colitis.
 [The possibilities of neuropsychological rehabilitation in multiple sclerosis].
 [Pseudoinfectious endocarditis].
Enter catalog number :