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Pubmed ID :16106194
Publication Date : //

Recurrent sarcoidosis in lung transplant allografts: granulomas are of recipient origin.


Sarcoidosis accounts for only 2.8% of lung transplants in the United States. It is, however, the most commonly reported disease to recur after lung transplantation. In most cases, recurrence is diagnosed as an incidental finding in transbronchial lung allograft biopsy (TBLAB) and is unrelated to clinical or radiologic abnormalities. The origin of the histiocytes composing the noncaseating granulomas in the allograft lung in patients with recurrent sarcoidosis (RS) was analyzed using DNA identity testing in 4 cases.

Authors : Ionescu Diana N , Hunt Jennifer L , Lomago Daren , Yousem Samuel A ,

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