Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :17039519
Publication Date : //

Eph-ephrin A system regulates murine blastocyst attachment and spreading.


Although numerous adhesion molecules are expressed on mammalian endometrial epithelial cells, there have not been any studies of a mechanism to prevent premature attachment of the embryo. In this study, we examined the possible involvement of Eph-ephrin interaction, which can induce repulsive forces. In mice, Eph A1, A2, and A4 were expressed on endometrial epithelial cells and ephrin A1-4 on blastocysts. Reverse transcriptase-polymerase chain reaction showed that mRNA expression of ephrin A1-4 on embryos transiently decreased around the implantation period. Immunohistochemistry demonstrated that the expression of Eph A1 on endometrial epithelial cells and ephrin A1 and A3 expression on embryos decreased at implantation sites. Recombinant Eph A1 reacted with cell the surface of ephrin A-bearing trophectoderm cells. Attachment assays using Eph A1-coated dishes showed that blastocyst attachment was reversibly inhibited by Eph A1. These findings suggest an important role of the Eph-ephrin A system in regulating the initial embryo-maternal contact during the cross-talk period that precedes embryo implantation.

Authors : Fujii Haruko , Tatsumi Keiji , Kosaka Kenzo , Yoshioka Shinya , Fujiwara Hiroshi , Fujii Shingo ,

Related products :

Catalog number Product name Quantity
804850 BSP31 LABEL ATTACHMENT SYSTEM EUROPE _ BSP31 LABEL ATTACHMENT SYSTEM EUROPE AM Proprietary Brady Systems;Pack-EA; 1 Pcs Per Pack
804851 BSP31 LABEL ATTACHMENT SYSTEM NamERICA _ BSP31 LABEL ATTACHMENT SYSTEM NamERICA AM Proprietary Brady Systems;Pack-EA; 1 Pcs Per Pack
25-707 POSTN binds to heparin. It induces cell attachment and spreading and plays a role in cell adhesion. POSTN may play a role in extracellular matrix mineralization. 0.05 mg
804850 BSP31 LABEL ATTACHMENT SYSTEM EUROPE 1
804851 BSP31 LABEL ATTACHMENT SYSTEM NAMERICA 1
30-330 Antp is a sequence-specific transcription factor which is part of a developmental regulatory system that regulates segmental identity in the mesothorax. It provides cells with specific positional iden 0.05 mg
W 4168.667.100 Anti-murine Ephrin-A1, Source: Monoclonal Rat, MAB 100
W 4169.667.100 Anti-murine Ephrin-A2, Source: Monoclonal Rat, MAB 100
W 4172.667.100 Anti-murine Ephrin-A4, Source: Monoclonal Rat, MAB 100
W 4173.667.100 Anti-murine Ephrin-B1, Source: Monoclonal Rat, MAB 100
W 4170.650.100 Anti-human Ephrin-A3, Source: Monoclonal Murine, MAB 100
W 4171.650.100 Anti-human Ephrin-A4, Source: Monoclonal Murine, MAB 100
W 4174.650.100 Anti-human Ephrin-B3, Source: Monoclonal Murine, MAB 100
ASM-5024 Blastocyst-Sure™ KSOM Embryo Culture Medium, without Phenol Red (with AA) 8 mL X 3 vials
ASM-5023 Blastocyst-Sure KSOM Embryo Culture Medium with Phenol Red (with AA) 8 mL X 3 vials
ASM-5023 Blastocyst-Sure™ KSOM Embryo Culture Medium, with Phenol Red (with AA) 8 mL X 3 vials
ASM-5024 Blastocyst-Sure KSOM Embryo Culture Medium without Phenol Red (with AA) 8 mL X 3 vials
orb81089 Human Ephrin B1 protein Ephrin B1 Human Recombinant (aa 136-347) expressed in E.coli, shows 47 kDa SDS-PAGE.The Ephrin B1 is purified by proprietary chromatographic techniques. For research use only. 2
orb81090 Human Ephrin B3 protein Ephrin B3 Human Recombinant (a.a. 135-341) expressed in E.coli, shows 47 kDa SDS-PAGE.The Ephrin B3 is purified by proprietary chromatographic techniques. For research use only 2
orb81088 Human Ephrin A4 protein Ephrin A4 Human Recombinant full length protein expressed in E.coli, shows 46 kDa SDS-PAGE (Icluding GST tag). The Ephrin A4 is purified by proprietary chromatographic techniqu 2
EIAAB38927 Gamma-soluble NSF attachment protein,Homo sapiens,Human,NAPG,N-ethylmaleimide-sensitive factor attachment protein gamma,SNAPG,SNAP-gamma
EIAAB38918 Alpha-soluble NSF attachment protein,Homo sapiens,Human,NAPA,N-ethylmaleimide-sensitive factor attachment protein alpha,SNAPA,SNAP-alpha
EIAAB38924 Beta-soluble NSF attachment protein,Homo sapiens,Human,NAPB,N-ethylmaleimide-sensitive factor attachment protein beta,SNAPB,SNAP-beta
EIAAB38922 Beta-soluble NSF attachment protein,Bos taurus,Bovine,NAPB,N-ethylmaleimide-sensitive factor attachment protein beta,SNAPB,SNAP-beta
EIAAB38926 Bos taurus,Bovine,Gamma-soluble NSF attachment protein,NAPG,N-ethylmaleimide-sensitive factor attachment protein gamma,SNAPG,SNAP-gamma


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur