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Pubmed ID :20849593
Publication Date : //

Rv1985c, a promising novel antigen for diagnosis of tuberculosis infection from BCG-vaccinated controls.


Antigens encoded in the region of difference (RD) of Mycobacterium tuberculosis constitute a potential source of specific antigens for immunodiagnosis. In the present study, recombinant protein Rv1985c from RD2 was cloned, expressed, purified, immunologically characterized and investigated for its potentially diagnostic value for tuberculosis (TB) infection among BCG-vaccinated individuals.

Authors : Chen Jiazhen , Wang Sen , Zhang Ying , Su Xiaodi , Wu Jing , Shao Lingyun , Wang Feifei , Zhang Shu , Weng Xinhua , Wang Honghai , Zhang Wenhong ,

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