Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :2144161
Publication Date : //

Antineoplastic effect of erbstatin on human mammary and esophageal tumors in athymic nude mice.


The growth of MCF-7, a human mammary carcinoma, in athymic nude mice was inhibited by intraperitoneal administration of erbstatin for 14 days in combination with an iron chelator, foroxymithine, which inhibits the decomposition of erbstatin. Another human mammary carcinoma, Br-10, was not affected. Foroxymithine alone had no anti-tumor activity. In four esophageal tumors, erbstatin retarded tumor growth. There were no side-effects in any erbstatin-treated group. Levels of epidermal growth factor receptors were not changed throughout treatment with erbstatin at any dose. Erbstatin, a tyrosine kinase inhibitor, may have an antineoplastic effect against human mammary and esophageal tumors.

Authors : Toi M , Mukaida H , Wada T , Hirabayashi N , Toge T , Hori T , Umezawa K ,

Related products :

Catalog number Product name Quantity
orb61213 AZD1152 AZD1152 was shown to be effective on SW620 tumors in nude mice after a single dose resulted in significant and durable inhibition of tumor growth. For research use only. 5 mg
EIAAB26611 Homo sapiens,Human,NDE1,Nuclear distribution protein nudE homolog 1,NudE,NUDE
EIAAB26613 mNudE,Mouse,Mus musculus,Nde1,Nuclear distribution protein nudE homolog 1,NudE,Nude
EIAAB26612 Nde1,Nuclear distribution protein nudE homolog 1,NudE,Nude,Nude1,Rat,Rattus norvegicus,rNudE
27-276 Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune sys 0.1 mg
677 Esophageal mucous chronic inflammation, esophageal intraepithelial neoplasia, esophageal cancer tissue array, including TNM, clinical stage and pathology grade, 60cases_ 120cores,
ASCITE-1 Custom Production of Ascites in Balb c mice (min 20 mice @$30 mice plus; $300 per cell line for cell culture) 1
GI_Esophagus - ESC1501 Esophageal cancer array consists of duplicated 70 cases of esophageal cancers of different grades and stages, and 5 cases of normal and other non_malignant esophageal tissues. 1.1 mm
29-688 As a tumor suppressor, it blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of a 0.1 mg
4-20483 Tumor Dissociation System 3 (Epithelial cancer and tumor, Mammary tumors), Mouse and Rat ea
GI_Esophagus - ESC961 Esophageal cancer array consists of duplicated 36 cases of esophageal cancer and 12 cases of normal and other non_malignant esophageal tissues. 1.5mm
ES809 Esophageal disease spectrum (esophageal cancer progression) tissue array, 78 cases_80 cores
PKI-ERBA-010 Erbstatin analog 10 mg
ES809 Esophageal disease spectrum (esophageal cancer progression) tissue array, 78 cases_80 cores; ihc Anti-Actin confirmed
MR-003 ///NEW Antibody 2-Step Effect Universal Anti-Mouse_ Anti-Rabbit IgG 2-Step Effect Universal 100ml
MR-003 ///NEW Antibody 2-Step Effect Universal Anti-Mouse_ Anti-Rabbit IgG 2-Step Effect Universal 50ml
ASCITE-1 Custom Production of Ascites in Balb_c mice (min 20 mice @$30_mice plus; $300 per cell line for cell culture) Species Reactivity: 1 Product tipe: Service
ASCITE-1 Custom Production of Ascites in Balb_c mice (min 20 mice @$30_mice plus; $300 per cell line for cell culture) 1
PKI-ERBA-010 Kinase inhibitors Erbstatin analog 10 mg
CSB-E08934Nu Nude mouse Alpha-fetoprotein,AFP ELISA Kit, Species Nude mouse, Sample Type serum, plasma 96T
CSB-E08935Nu Nude mouse cyclooxygenase-2,COX-2 ELISA kit, Species Nude mouse, Sample Type serum, plasma 96T
Z7020029 Esophageal Tumor Tissue Array _ Duplicated 36 cases of esophageal cancer and 12 cases of normal and other non_malignant 5 slides
Z7020029 Esophageal Tumor Tissue Array _ Duplicated 36 cases of esophageal cancer and 12 cases of normal and other non_malignant 5 slides
Z7020026 Esophageal Tumor Tissue Array - 70 cases of esophageal cancers of different grades and stages, and 5 cases of normal and 5 slides
Z7020026 Esophageal Tumor Tissue Array _ 70 cases of esophageal cancers of different grades and stages, and 5 cases of normal and 5 slides


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur