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Pubmed ID :23100146
Publication Date : //

Differential reactivity to IMPDH2 by anti-rods/rings autoantibodies and unresponsiveness to pegylated interferon-alpha/ribavirin therapy in US and Italian HCV patients.


Autoantibodies to cytoplasmic structures called rods and rings (RR) are primarily specific to patients with hepatitis C virus (HCV) infection treated with pegylated interferon-alpha/ribavirin (IFN/R). Our aim is to examine anti-RR antibodies specificity and correlation with the response to IFN/R therapy in two independent cohorts (US and Italy) of HCV patients.

Authors : Carcamo Wendy C , Ceribelli Angela , Calise S John , Krueger Claire , Liu Chen , Daves Massimo , Villalta Danilo , Bizzaro Nicola , Satoh Minoru , Chan Edward K L ,

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