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Pubmed ID :24826884
Publication Date : 2014/06/13

Interlude of cGMP and cGMP/protein kinase G type 1 in pancreatic adenocarcinoma cells.


cAMP and cGMP signaling is important both for normal and cancer cells. This signaling is controlled by adenylyl and guanylyl cyclases and cyclic nucleotide phosphodiesterases. One of the direct targets for cGMP is protein kinase G (PKG). The main aim of this work was to investigate cGMP and PKG signaling in pancreatic adenocarcinoma (PDAC) cells.

Authors : Karakhanova Svetlana , Golovastova Marina , Philippov Pavel P , Werner Jens , Bazhin Alexandr V ,

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