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Pubmed ID :25791936
Publication Date : //

Involvement of Bim in Photofrin-mediated photodynamically induced apoptosis.


Photodynamic therapy (PDT) is a promising noninvasive technique, which has been successfully applied to the treatment of human cancers. Studies have shown that the Bcl-2 family proteins play important roles in PDT-induced apoptosis. However, whether Bcl-2-interacting mediator of cell death (Bim) is involved in photodynamic treatment remains unknown. In this study, we attempt to determine the effect of Bim on Photofrin photodynamic treatment (PPT)-induced apoptosis in human lung adenocarcinoma ASTC-a-1 cells.

Authors : Wang Xianwang , He Xiaobing , Hu Shujuan , Sun Anbang , Lu Chengbiao ,

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