Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :26980696
Publication Date : //

MBD1 is an Epigenetic Regulator of KEAP1 in Pancreatic Cancer.


MBD1 (Methyl-CpG Binding Domain Protein 1) is highly expressed in pancreatic cancer. Nrf2 (NF-E2 p45-related factor 2) and the 'antioxidant response element' (ARE)-driven genes that NRF2 controls are frequently upregulated in pancreatic cancer and correlate with poor survival. Keap1 (Kelch-like ECH-associated protein 1) is a dominant negative regulator of NRF2 and is reported to be epigenetically regulated by promoter methylation. However, the role of MBD1 with antioxidant response and its association with KEAP1 has never been reported before and remains unclear.

Authors : Zhang B , Xu J , Li C , Shi S , Ji S , Xu W , Liu J , Jin K , Liang D , Liang C , Liu L , Liu C , Qin Y , Yu X ,

Related products :

Catalog number Product name Quantity
Pancreas - PAC481 Pancreatic cancer tissue array contains 20 cases of pancreatic cancers and 4 cases of normal and non_malignant pancreatic tissues. 2mm
orb61244 Erlotinib Erlotinib hydrochloride is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. For research use only. 100 mg
PA207b High_density (69 cases_207 cores), multiple pancreatic cancer (I_4 grade) and normal pancreatic tissue array BLOCK
PA207 High_density (69 cases_207 cores), multiple pancreatic cancer (1_3 grade) and normal pancreatic tissue array, replaced by PA2072
PA2081 Pancreatic disease spectrum (pancreatic cancer progression) tissue array with pathology grade and TNM information, 101 cases_208 cores
PA2081 Pancreatic disease spectrum (pancreatic cancer progression) tissue array with pathology grade and TNM information, 101 cases_208 cores; ihc Anti-Actin confirmed
PA207b High-density (69 cases_207 cores), multiple pancreatic cancer (I-4 grade) and normal pancreatic tissue array block; ihc Anti-Cytokeratin (CK) confirmed
PA207 High-density (69 cases_207 cores), multiple pancreatic cancer (1-3 grade) and normal pancreatic tissue array, replaced by PA2072; ihc Anti-Cytokeratin (CK) confirmed
orb60366 Isotretinoin It was developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more. For research use only. 1 g
1442 Pancreatic cancer tissue array with normal pancreatic tissue, including TNM, clinical stage and pathology grade, 96 cases_96 cores, replacing PA961
T143 Pancreatic cancer test tissue array, with normal pancreatic tissue as control, including TNM, clinical stage and pathology grade, 2 serial sections, 6 cases_24 cores
PA961a Pancreatic cancer tissue array with normal pancreatic tissue, including TNM, clinical stage and pathology grade, 96 cases_96 cores, replacing PA961; ihc Anti-Actin confirmed
T143 Pancreatic cancer test tissue array, with normal pancreatic tissue as control, including TNM, clinical stage and pathology grade, 2 serial sections, 6 cases_24 cores; ihc Anti-Actin confirmed
26-109 DLG7 is a potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. It is a mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. DLG7 is the key regulator 0.05 mg
A1820 KEAP1 Primary Antibody, KEAP1, Species: Human Recombinant Protein Source: Rabbit Polyclonal 50ug
51-003 removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism. DNA methylation involves the addition of a 100 ug
A2227 MBD1 Primary Antibody, MBD1, Species: Human Synthetic peptide Source: Rabbit Polyclonal 100ug
3281BP-50 MBD1 Blocking Peptide target: MBD1 50 μg
PAC481-1 Pancreatic Cancer tissue array 1x (6x8)
PAC481-5 Pancreatic Cancer tissue array 5x (6x8)
DPCCI-123-V Human Sample (Pancreatic Cancer) Individual 1 unit
MG-0024-50 Pancreatic Cancer Stem Cell Multiplex PCR 50
BMDEU1024 CA_242, Gastric & Pancreatic Cancer, ELISA Kit kit
BMDEU1023 CA_19_9, Gastric & Pancreatic Cancer, ELISA Kit kit
PAC1021 Pancreatic cancer tissue array, 102 cases (1.5mm) 102 Cases


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur