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Pubmed ID :27564840
Publication Date : //

Reduced Osteoarthritis Severity in Aged Mice With Deletion of Macrophage Migration Inhibitory Factor.


Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that is elevated in the serum and synovial fluid of patients with osteoarthritis (OA). This study was undertaken to investigate the potential role of MIF in OA in human joint tissues and in vivo in mice with age-related and surgically induced OA.

Authors : Rowe Meredith A , Harper Lindsey R , McNulty Margaret A , Lau Anthony G , Carlson Cathy S , Leng Lin , Bucala Richard J , Miller Richard A , Loeser Richard F ,

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