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Pubmed ID :27818935
Publication Date : //

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing expression.


The transcription factor cyclic AMP-responsive element-binding protein H (CREBH, encoded by ) is highly expressed in the liver and small intestine. Hepatic CREBH contributes to glucose and triglyceride metabolism by regulating fibroblast growth factor 21 () expression. However, the intestinal CREBH function remains unknown.

Authors : Kikuchi Takuya , Orihara Kana , Oikawa Fusaka , Han Song-Iee , Kuba Motoko , Okuda Kanako , Satoh Aoi , Osaki Yoshinori , Takeuchi Yoshinori , Aita Yuichi , Matsuzaka Takashi , Iwasaki Hitoshi , Yatoh Shigeru , Sekiya Motohiro , Yahagi Naoya , Suzuki Hiroaki , Sone Hirohito , Nakagawa Yoshimi , Yamada Nobuhiro , Shimano Hitoshi ,

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