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Pubmed ID :28681171
Publication Date : //

A randomized phase II trial of ridaforolimus, dalotuzumab, and exemestane compared with ridaforolimus and exemestane in patients with advanced breast cancer.


To evaluate whether adding humanized monoclonal insulin growth factor-1 receptor (IGF-1R) antibody (dalotuzumab) to mammalian target of rapamycin (mTOR) inhibitor (ridaforolimus) plus aromatase inhibitor (exemestane) improves outcomes in patients with estrogen receptor (ER)-positive advanced/metastatic breast cancer.

Authors : Rugo Hope S , Trédan Olivier , Ro Jungsil , Morales Serafin M , Campone Mario , Musolino Antonino , Afonso Noémia , Ferreira Marta , Park Kyong Hwa , Cortes Javier , Tan Antoinette R , Blum Joanne L , Eaton Lamar , Gause Christine K , Wang Zhen , Im Ellie , Mauro David J , Jones Mary Beth , Denker Andrew , Baselga José ,

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