Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :28816963
Publication Date : 2017/08/17

Efficacy and safety evaluation of fludarabine-based chemotherapy regimen for patients with non-Hodgkin lymphoma: A meta-analysis.


This meta-analysis was performed to evaluate the efficacy and safety of fludarabine (F)-based regimen for the treatment of non-Hodgkin lymphoma (NHL) compared with other regimens with no F contained.PubMed, Embase, Cochrane Library, Wanfang, VIP, and CNKI databases were searched to identify eligible literatures. R software version 3.12 was used for statistical analysis. Odds ratio (OR) with 95% confidence interval (CI) were utilized to express the complete response, overall response and adverse events outcomes. Egger test was carried out to examine the publication bias and sensitivity analysis was performed to evaluate the stability of our results.Twelve eligible literatures consisting of 1587 patients were included in this study. Greater complete response (OR = 1.66, 95% CI: 0.98-2.80) and overall response (OR = 1.38, 95% CI: 0.85-2.24) were found for patients who received F-based regimen than those received other regimens, although the results were not statistically significant. In addition, F-based regimen was associated with significantly lower risk of adverse events compared with other regimens (OR = 0.46, 95% CI: 0.28-0.74). Results of subgroup analysis showed that significantly lower incidence was presented only for constipation among the 7 specific adverse events (OR = 0.03, 95% CI: 0.01-0.14).F-based chemotherapy regimen was an effective and well-tolerated treatment for patients with NHL.

Authors : Zhang Xiaoping , Ge Zheng , Chen Baoan , Liu Ran , Gao Chong ,

Related products :

Catalog number Product name Quantity
orb60465 Fludarabine Fludarabine(Fludara) is a purine analog and a chemotherapy drug with IC50 < 3 50 mg
LM802 Lymphoma (Hodgkin's and non-Hodgkin's disease) tissue array, 80 cases_80 cores, replaced by NHL803; ihc Anti-Leukocyte Common Antigen (LCA) confirmed
LM208 High density tissue microarray of Hodgkin's Disease, Non-Hodgkin's lymphoma and normal lymph node tissues, 69 cases_208 cores; ihc Anti-Actin confirmed
LM801 Lymphoma (Hodgkin's and non-Hodgkin's disease) tissue array, 80 cases_80 cores, replaced by LM801a; ihc Anti-Proliferating Cell Nuclear Antigen (PCNA) confirmed
orb60253 Fludarabine Phosphate Fludarabine Phosphate (Fludara, 2-F-ara-AMP, FAMP) is a nucleoside analogue and formulated as the monophosphate form of F-ara-AMP(fludarabine, IC50 < 3 50 mg
orb61263 MGCD0103 Mocetinostat (MGCD0103) is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers including follicular lymphoma, Hodgkin's lymphoma and acute my 10 mg
1332 non-Hodgkin's Lymphoma Tumor Lysate 0.5 mg
1332 non-Hodgkin's Lymphoma Tumor Lysate 1.0 mg
1332 non-Hodgkin's Lymphoma Tumor Lysate 0.1 mg
CS20-01-003 Hodgkin\'s Lymphoma tissue array 6 x 10
CS20-01-003 Hodgkin\'s Lymphoma tissue array 6 x 10
CS20-01-003 Hodgkin\'s Lymphoma tissue array 6 x 10
37-057-230125 Human Tumor Tissue Lymphoma. Non-Hodgkin's 1 mg
'CS20-01-003 Hodgkin's Lymphoma tissue array tissues 6 x 10
1332 Human non-Hodgkin's Lymphoma Tumor Lysate 0.1 mg
37-057-230124 Human Tumor Tissue Lymphoma. Hodgkin's 1 mg
37-057-230651 Human Tumor Tissue Lymphoma. Hodgkin's Disease 0.1 mg
37-057-230827 Human Tumor Tissue Lymphoma. Hodgkin's Disease 0.1 mg
37-057-230828 Human Tumor Tissue Lymphoma. Non-Hodgkin's Disease 0.1 mg
37-057-230652 Human Tumor Tissue Lymphoma. Non-Hodgkin's Disease 0.1 mg
HL801 Hodgkin's lymphoma tissue array, 45 cases_80 cores
37-057-231017 Human Tumor Tissue Lymphoma. Hodgkin's Disease 0.5 mg
37-057-231018 Human Tumor Tissue Lymphoma. Non-Hodgkin's Disease 0.5 mg
NB820-59434 Human Tumor Tissue Lymphoma, Hodgkin\\\\\\\'s 1 mg
'CS20-00-002 Human Lymphoma tissue array (Diffuse large cell B-cell T-cell Hodgkin lymphoma follicular diffuse B-cell, etc.) tissues 7 x 9


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur