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Pubmed ID :28982901
Publication Date : //

Association Between Interleukin-10 Receptors and the CD45-Immunophenotype of Central Nervous System Tumors: A Preliminary Study.


One of the current hypotheses assumes that brain tumors exert an immunosuppressive influence on the surrounding cellular environment. Interleukin-10 (IL-10) is one of the immunosuppressive cytokines modifying the biological activity of cancer. The aim of this study was to assess the expression of IL10R in CD45+ cells within primary brain tumors and metastases and establish its association with tumor basic immunophenotype.

Authors : Zadka Lukasz , Kram Pawel , Koscinski Jeremi , Jankowski Roman , Kaczmarek Mariusz , Piatek Katarzyna , Kulus Michal , Gomułkiewicz Agnieszka , Piotrowska Aleksandra , Dziegiel Piotr ,

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