Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :29034741
Publication Date : 2017/10/16

Anti-inflammatory effect of methanolic extract of Gmelina arborea bark and its fractions against carrageenan induced paw oedema in rats.


Gmelina arborea has been traditionally used for treatment of abdominal pain, burning sensation and as stomachic. The anti-inflammatory effect of aqueous and methanol extract of this plant has been studied but detailed investigations on anti-inflammatory activity of G. arborea stem bark are still not available. Therefore, the present study was designed to evaluate the anti-inflammatory activity of methanol extract and its fractions using carrageenan induced paw oedema model. Methanol extract at the dose of 500 mg/kg and its ethyl acetate fraction at 50 mg/kg showed significant reduction in paw oedema in comparison with standard drug. Ethyl acetate fraction was subjected to column chromatography which resulted in isolation of a new flavonoid (GM-01). Anti-inflammatory effect of methanol extract and its fractions can be attributed to the presence of the flavonoid GM-01. Further studies are underway for evaluation of anti-inflammatory effect of GM-01 and identification of active constituents present in ethyl acetate fraction.

Authors : Kaur Sarabjit , Bedi Preet Mohinder Singh , Kaur Navreet ,

Related products :

Catalog number Product name Quantity
8011-48-1 Pine Bark Extract Pine Bark Extract 1g
GTX80881 UBC Fractions Extract 400 µg
FRA270 Hepatic S9 fractions Male Sprague Dawley rat, b-naphthoflavone and phenobarbital induced 10 mg/Vial
FRA270 Male Sprague Dawley rat, b-naphthoflavone and phenobarbital induced Hepatic S9 fractions Vial containing 10 mg of proteins
FRA270 Male Sprague Dawley rat, b-naphthoflavone and phenobarbital induced Hepatic S9 fractions Vial containing 10mg of proteins
900-07-1 Carrageenan commercial grade Carrageenan commerci 1g
6923 Accessory for "fixed" rear side multiple fractions (up to more than 18 fractions)
6923 OMNICOLL fraction collector_sampler, programmable accessories: Accessory for "fixed" rear side multiple fractions (up to more than 18 fractions)
MR-003 ///NEW Antibody 2-Step Effect Universal Anti-Mouse_ Anti-Rabbit IgG 2-Step Effect Universal 100ml
MR-003 ///NEW Antibody 2-Step Effect Universal Anti-Mouse_ Anti-Rabbit IgG 2-Step Effect Universal 50ml
1107-400 Jurkat Cell Extract (Induced) 400 ìg
1107-400 Jurkat Cell Extract (Induced) 400 μg
1107-400 Jurkat Cell Extract (Induced)400 ug 400 ug
1107-400 Jurkat Cell Extract (Induced) 400 ug
1107-1000 Jurkat Cell Extract (Induced)1 mg 1 mg
1107-1000 Jurkat Cell Extract (Induced) 1 mg
758-08-7 2_Mercaptoacetamide methanolic ammonia s 1g
MH2050 Non Aqueous Titrant 0.5N Methanolic HCI 2.5l
MH2050 Non Aqueous Titrant 0.5N Methanolic HCI 2.5L
84650-55-5 Buckthorn Bark Buckthorn Bark 1g
9061-82-9 Sodium Carrageenan Sodium Carrageenan 1g
FRA284 Hepatic XXX S9 Fractions Hepatic S9 fractions Vial containing 10 mg of proteins
FRA284 Hepatic XXX S9 Fractions Hepatic S9 fractions
orb60883 Gynostemma Extract Gynostemma Extract is a saponins extract derived from the Gynostemma pentaphyllum. For research use only. 10 mg
A01734B Extractable Nuclear Antigen (ENA) Extract(blank) Extract 0.25mL


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur