Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :29051322
Publication Date : 2017/10/20

A multicenter phase I study evaluating dual PI3K and BRAF inhibition with PX-866 and vemurafenib in patients with advanced BRAF V600 mutant solid tumors.


The objectives of the study were to evaluate the safety of daily oral PX-866 in combination with twice daily vemurafenib and to identify potential predictive biomarkers for this novel combination.

Authors : Yam Clinton , Xu Xiaowei , Davies Michael A , Gimotty Phyllis A , Morrissette Jennifer Jd , Tetzlaff Michael T , Wani Khalida , Liu Shujing , Deng Wanleng , Buckley Meghan , Zhao Jianhua , Amaravadi Ravi K , Haas Naomi , Kudchadkar Ragini R , Pavlick Anna , Sosman Jeffrey A , Tawbi Hussein , Walker Luke , Schuchter Lynn M , Karakousis Giorgos C , Gangadhar Tara C ,

Related products :

Catalog number Product name Quantity
ADx-BR04 AmoyDx BRAF V600 _ 24 Kit size (test/kit)
orb61284 PLX4032 PLX4032 is a highly selective inhibitor of BRAF kinase, with an IC50 of 44 nM against V600E-mutant BRAF. For research use only. 5 mg
ADx-BR04-RG72 AmoyDx BRAF V600 _" 24 Kit size (test/kit)
DL-BRAF-Hu Human B-Raf Proto Oncogene Serine_Threonine Protein Kinase (BRAF) ELISA Kit 96T
DP0070 BRAF(phospho S601) & BRAF Protein Phosphorylation Antibody Pair 1 Set
DP0064 BRAF(phospho T439) & BRAF Protein Phosphorylation Antibody Pair 1 Set
DP0052 BRAF(phospho S445) & BRAF Protein Phosphorylation Antibody Pair 1 Set
BRAF-253H Protein: Recombinant Human BRAF, GST-tagged, Active 5μg
BRAF-253H Protein Recombinant Human BRAF, GST-tagged, Active 5μg
DL-BRAF-Hu Human B-Raf Proto Oncogene Serine-Threonine Protein Kinase (BRAF) ELISA Kit 96T
A2988 BRAF Primary Antibody, BRAF, Species: Human Synthetic peptide Source: Rabbit Polyclonal 50ug
AP0012 Phospho-BRAF-S445 Primary Antibody, BRAF, Species: Human Synthetic peptide Source: Rabbit phosphorylation 50ug
GWB-BFDBFE Proto-Oncogene Serine_Threonine Protein Kinase BRAF (BRAF) Rabbit anti-Human Polyclonal (pThr598_Ser601) Antibody
MAB - 606020108 Monoclonal Antibodies: BRAF; reactive species: human; Clone: 1H12F1, 1H12G10,1F12F11C9; Isotype: IgG1; Specificity: BRAF 0.1ml
GWB-BFDBFE Proto-Oncogene Serine Threonine Protein Kinase BRAF (BRAF) Rabbit anti-Human Polyclonal (pThr598 Ser601) Antibody
orb61216 AZD6244 Activating mutations in the BRAF gene, primarily at V600E, are associated with poorer outcomes in patients with papillary thyroid cancer. For research use only. 500 mg
AP0012 Phospho BRAF (S445)Phospho-Polyclonal Antibody, Reactivity: H M R, Gene ID: 673, Synonyms: BRAF 200ug
AP0012 Phospho BRAF (S445)Phospho-Polyclonal Antibody, Reactivity: H M R, Gene ID: 673, Synonyms: BRAF 100ug
LF-MA41733 Anti-BRAF (1H12), Mouse Monoclonal to BRAF, Isotype IgG1, Host Mouse 50
Path-GT-QU-BRAF-V600E quasa Real-time PCR Genotyping kit for BRAF (V600E) 50 reactions)
AO1257a BRAF Antibody Mouse Monoclonal Antibody to BRAF Applications WB, IHC, IF, E 0.1ml
AO1088a BRAF Antibody Mouse Monoclonal Antibody to BRAF Applications WB, IHC, E 0.1ml
DL-BRAF-Hu BRAF ELISA kit 96T
LF-PA40155 anti-BRAF (phospho-Thr598_Ser601), Rabbit polyclonal to BRAF (phospho-Thr598_Ser601), Isotype IgG, Host Rabbit 50 ul
orb61211 Axitinib Axitinib is currently in phase I to III development in a range of solid tumors. For research use only. 100 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur