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Pubmed ID :29058042
Publication Date : //

Chronic N-acetylcysteine treatment alleviates acute lipopolysaccharide-induced working memory deficit through upregulating caveolin-1 and synaptophysin in mice.


Working memory (WM) is a dynamic encoding process and an active representation of information over a short time. The ability to guide forthcoming behavior would be disrupted if WM was impaired by various factors including inflammation, stress, free radicals, and disease states such as schizophrenia. However, the mechanism underlying acute working memory impairment remains to be defined.

Authors : Shen Xianzhi , Sun Yanyun , Wang Mengwei , Shu Hui , Zhu Li-Juan , Yan Pei-Yun , Zhang Jun-Fang , Jin Xinchun ,

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