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Pubmed ID :29059438
Publication Date : //

Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor.


Neuroblastoma (NB) is the most common solid tumor found in children, and deletions within the 11q region are observed in 11% to 48% of these tumors. Notably, such tumors are associated with poor prognosis; however, little is known regarding the molecular targets located in 11q.

Authors : Takagi Masatoshi , Yoshida Misa , Nemoto Yoshino , Tamaichi Hiroyuki , Tsuchida Rika , Seki Masafumi , Uryu Kumiko , Nishii Rina , Miyamoto Satoshi , Saito Masahiro , Hanada Ryoji , Kaneko Hideo , Miyano Satoru , Kataoka Keisuke , Yoshida Kenichi , Ohira Miki , Hayashi Yasuhide , Nakagawara Akira , Ogawa Seishi , Mizutani Shuki , Takita Junko ,

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