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Complete Remission of Advanced Gastric Cancer in Response to Chemotherapy With Docetaxel, Cisplatin and Capecitabine (dcx).
We describe the case of a 60 year-old man with advanced gastric cancer. The patient started chemotherapy with a combination of docetaxel, cisplatin and capecitabine. In a radiological assessment after the third treatment cycle, a significant reduction of adenopathies and gastric wall thickening was observed. Partial remission was maintained until the end of the chemotherapy (6 cycles). The follow-up evaluations indicated the radiological remission was maintained and that there was a reduction of gastric wall thickening and normalisation of remote lymph nodes. After 43 months since the final treatment cycle, the patient remains progression-free.
Authors : Marroqui Asuncion Juarez , Ferrandiz Cristina Llorca , Escalante Sonia Macia , Molla Sara Blasco , Ortega Dolores Garcia ,
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Pathways :
WP2361: Gastric cancer network 1
WP2363: Gastric cancer network 2
WP1040: Inflammatory Response Pathway
WP1113: Cytokines and Inflammatory Response
WP1156: Inflammatory Response Pathway
WP1527: stress response
WP1530: miRNA regulation of DNA Damage Response
WP1579: DNA damage response
WP1589: Folate-Alcohol and Cancer Pathway
WP1781: Advanced glycosylation endproduct receptor signaling
WP1903: Response to elevated platelet cytosolic Ca2+
WP1939: Unfolded Protein Response
WP1968: genetic alternations of lung cancer
WP1971: Integrated Cancer pathway
WP1984: Integrated Breast Cancer Pathway
WP2087: miRNA regulation of DNA Damage Response
WP2107: pathways in human cancer
WP2152: BDNF
WP222: Cytokines and Inflammatory Response (BioCarta)
WP2256: Integrated Pancreatic Cancer Pathway
WP2263: Prostate Cancer
WP2291: Deregulation of Rab and Rab Effector Genes in Bladder Cancer
WP2335: sGC Cancer
WP2367: Private Pancreatic Cancer
WP2377: Integrated Pancreatic Cancer Pathway
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[CPPED1 CSTP1] Serine/threonine-protein phosphatase CPPED1 (EC 3.1.3.16) (Calcineurin-like phosphoesterase domain-containing protein 1) (Complete S-transactivated protein 1)
[L3] Pre-protein VI (pVI) [Cleaved into: Protease cofactor (pVI-C); Endosome lysis protein]
[L3] Protease (EC 3.4.22.39) (Adenain) (Adenovirus protease) (AVP) (Adenovirus proteinase) (Endoprotease)
[IVa2] Packaging protein 1 (Packaging protein IVa2)
[L2] Pre-histone-like nucleoprotein (Pre-core protein VII) (pVII) [Cleaved into: Histone-like nucleoprotein (NP) (Core protein VII)]
[L4] Shutoff protein (100 kDa protein) (p100K) (100K-chaperone protein) (L4-100K) (Shutoff protein 100K)
[E2A DBP] DNA-binding protein (DBP) (Early 2A protein) (Early E2A DNA-binding protein)
[L1] Pre-hexon-linking protein IIIa (Capsid vertex-specific component IIIa) (CVSC) (Protein IIIa) (pIIIa) [Cleaved into: Hexon-linking protein IIIa]
[L4] Pre-hexon-linking protein VIII (Pre-protein VIII) (pVIII) [Cleaved into: Hexon-linking protein-N (Protein VIII-N) (12.1 kDa protein VIII); Hexon-linking protein-C (7.6 kDa protein VIII) (Protein VIII-C)]
[E2B POL] DNA polymerase (EC 2.7.7.7)
[E1B IX pIX] Hexon-interlacing protein (Protein IX)
[L2] Penton protein (CP-P) (Penton base protein) (Protein III)
[L1] Packaging protein 3 (L1-52/55 kDa protein) (Packaging protein 52K)
[L3] Hexon protein (CP-H) (Protein II)
[E1B] E1B protein, small T-antigen
[E1A] Early E1A protein
[E1A] Early E1A protein
[CAGGBEG34_30031] Family:IS4, Group:IS50 transposase (Complete) (EC 3.1.-.-)
[BN811_00416] Methanoculleus bourgensis MS2 complete genome
[BN577_00003] Methanoculleus bourgensis MS2 complete genome
[XDD1_3571] Complete genome segment 12/17
[HALO1618] Complete genome segment 7/17
[EBH_0035860] Chromosome III, complete sequence, related
[EAH_00039850] Chromosome III, complete sequence, related
[ENH_00064080] Chromosome III, complete sequence, related
[EMWEY_00030520] Chromosome III, complete sequence, related
[ETH_00005000] Chromosome III, complete sequence, related
[EAH_00021870] Chromosome I, complete genome, related
[CAGGBEG34_380010] Family:IS4, Group: IS50 transposase (Complete) (EC 3.1.-.-)
[EBH_0041250] Chromosome II, complete genome, related
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