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Novel Functional Role of Heat Shock Protein 90 in Mitochondrial Connexin 43-Mediated Hypoxic Postconditioning.
Previous studies have shown that heat shock protein 90 (HSP90)-mediated mitochondrial import of connexin 43 (Cx43) is critical in preconditioning cardioprotection. The present study was designed to test whether postconditioning has the same effect as preconditioning in promoting Cx43 translocation to mitochondria and whether mitochondrial HSP90 modulates this effect.
Authors : Tu Rong-Hui , Li Qing-Jie , Huang Zheng , He Yan , Meng Jian-Jun , Zheng Hui-Lei , Zeng Zhi-Yu , Zhong Guo-Qiang ,
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Pathways :
WP1502: Mitochondrial biogenesis
WP2292: Chemokine signaling pathway
WP525: Mitochondrial Unfolded-Protein Response
WP1049: G Protein Signaling Pathways
WP1069: Integrin-mediated cell adhesion
WP1107: Mitochondrial LC-Fatty Acid Beta-Oxidation
WP1108: Hypothetical Network for Drug Addiction
WP1165: G Protein Signaling Pathways
WP1185: Integrin-mediated cell adhesion
WP1226: Mitochondrial LC-Fatty Acid Beta-Oxidation
WP1246: Hypothetical Network for Drug Addiction
WP1263: Mitochondrial Gene Expression
WP1281: Hypothetical Network for Drug Addiction
WP1301: Mitochondrial Gene Expression
WP1368: Mitochondrial Gene Expression
WP1371: G Protein Signaling Pathways
WP1386: Integrin-mediated cell adhesion
WP1438: Influenza A virus infection
WP1493: Carbon assimilation C4 pathway
WP1531: Vitamin D synthesis
WP1566: Citrate cycle (TCA cycle)
WP1613: 1,4-Dichlorobenzene degradation
WP1616: ABC transporters
WP1624: Bacterial secretion system
WP1625: Base excision repair
Related Genes :
Bibliography :
[29179175] Novel Functional Role of Heat Shock Protein 90 in Mitochondrial Connexin 43-Mediated Hypoxic Postconditioning.
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